OSLO, Norway, June 6, 2019 /PRNewswire/ -- Nordic Nanovector
ASA (OSE: NANO) announces that its Chief Scientific Officer,
Jostein Dahle, will present results
from preclinical studies with 212PB-NNV003, a novel Targeted Alpha
Therapy comprising its proprietary CD37-specific antibody (NNV003)
coupled with the alpha-particle generating radioisotope lead-212
(212Pb) in models of chronic lymphocytic leukaemia (CLL) and
non-Hodgkin lymphoma (NHL) at the Targeted Radiopharmaceuticals
Summit taking place in Munich,
Germany on 12-13 June.
The presentation will take place at 13th June 09:30-10:00 CEST and is entitled:
Targeted alpha therapy with 212Pb-NNV003 for the treatment of
CD37 positive B-cell chronic lymphocytic leukaemia (CLL) and
non-Hodgkin lymphoma (NHL)
CD37 is highly and selectively expressed on the surface of
mature B lymphocytes and B-cell malignancies and may become a
useful alternative to the CD20 target, due to the emergence of
resistance to anti-CD20 therapies.
Alpha-emitting radionuclides have demonstrated good potential
for cancer targeted therapies because of short-range alpha energy
deposition (50–100 µm) that causes irreparable DNA double-strand
breaks and localized cytotoxicity while sparing surrounding healthy
tissues.
The targeted alpha therapy 212Pb-NNV003 has been developed under
a collaboration between Nordic Nanovector and Orano Med.
For further information, please contact:
IR
enquiries
Malene Brondberg
VP Investor Relations and Corporate Communications
Cell: +44-7561-431-762
Email: ir@nordicnanovector.com
International Media Enquiries
Mark Swallow/David
Dible (Citigate Dewe Rogerson)
Tel: +44-207-638-9571
Email: nordicnanovector@citigatedewerogerson.com
About Nordic Nanovector
Nordic Nanovector is committed to develop and deliver innovative
therapies to patients to address major unmet medical needs and
advance cancer care. The Company aspires to become a leader in the
development of targeted therapies for haematological cancers.
Nordic Nanovector's lead clinical-stage candidate is Betalutin®,
a novel CD37-targeting radioimmunotherapy designed to advance the
treatment of non-Hodgkin's lymphoma (NHL). NHL is an indication
with substantial unmet medical need, representing a growing market
forecast to be worth nearly USD 29
billion by 2026. Nordic Nanovector intends to retain
marketing rights and to actively participate in the
commercialisation of Betalutin® in core markets.
Further information can be found at www.nordicnanovector.com
Forward-looking statements
This press release contains certain forward-looking
statements. These statements are based on management's current
expectations and are subject to uncertainty and changes in
circumstances, since they relate to events and depend on
circumstances that will occur in the future and which, by their
nature, will have an impact on Nordic Nanovector's business,
financial condition and results of operations. The terms
"anticipates", "assumes", "believes", "can", "could", "estimates",
"expects", "forecasts", "intends", "may", "might", "plans",
"should", "projects", "targets", "will", "would" or, in each case,
their negative, or other variations or comparable terminology are
used to identify forward-looking statements. These forward-looking
statements are not historic facts. There are a number of factors
that could cause actual results and developments to differ
materially from those expressed or implied in the forward-looking
statements. Factors that could cause these differences include, but
are not limited to, risks associated with implementation of Nordic
Nanovector's strategy, risks and uncertainties associated with the
development and/or approval of Nordic Nanovector's product
candidates, ongoing and future clinical trials and expected trial
results, the ability to commercialise Betalutin®, technology
changes and new products in Nordic Nanovector's potential market
and industry, Nordic Nanovector's freedom to operate (competitors
patents) in respect of the products it develops, the ability to
develop new products and enhance existing products, the impact of
competition, changes in general economy and industry conditions,
and legislative, regulatory and political factors. No assurance can
be given that such expectations will prove to have been correct.
Nordic Nanovector disclaims any obligation to update or revise any
forward-looking statements, whether as a result of new information,
future events or otherwise.
This information is subject to a duty of disclosure pursuant
to Section 5-12 of the Securities Trading Act.
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SOURCE Nordic Nanovector