PCI Biotech: Publication of preclinical tuberculosis results
11 Enero 2022 - 02:01AM
PCI Biotech: Publication of preclinical tuberculosis results
Oslo (Norway), 11 January 2022 – PCI Biotech (OSE: PCIB), a
cancer focused biopharmaceutical company, today announced that
results from preclinical studies on tuberculosis performed in
collaboration with The University of Zurich and ETH Zurich are
accepted for publication in Frontiers in Immunology, a high impact
immunology journal. The article title is "Photochemically-mediated
inflammation and cross-presentation of Mycobacterium bovis BCG
proteins stimulates strong CD4 and CD8 T-cell responses in mice”
and the abstract of the publication is available through this link:
www.frontiersin.org/articles/10.3389/fimmu.2022.815609/abstract.
Anders Høgset, CSO of PCI Biotech, comments:
“Infectious diseases are not within PCI Biotech’s core focus areas,
but these positive results support our general understanding of
fimaVacc’s mode of action and further demonstrate the broad
potential of the technology.”
Contact
information: Per
Walday, CEOpw@pcibiotech.noMobile: +47 917 93 429
About PCI
Biotech PCI
Biotech is a biopharmaceutical late-stage clinical development
company focusing on development and commercialisation of novel
therapies for the treatment of cancer through its innovative
photochemical internalisation (PCI) technology platform. PCI is
applied to three distinct anticancer paradigms:
fimaChem (enhancement of
chemotherapeutics for localised treatment of cancer),
fimaVacc (T-cell induction
technology for therapeutic vaccination), and
fimaNAc (nucleic acid
therapeutics delivery).
Photochemical internalisation induces triggered
endosomal release that is used to unlock the true potential of a
wide array of therapeutic modalities. The company’s lead programme
fimaChem consists of
a pivotal study in bile duct cancer, an orphan indication with
a high unmet need and without approved products.
fimaVacc applies a unique mode of
action to enhance the essential cytotoxic effect of therapeutic
cancer vaccines, which works in synergy with several other
state-of-the-art vaccination technologies.
fimaNAc utilises the endosomal
release to provide intracellular delivery of nucleic acids, such as
mRNA and RNAi therapeutics, thereby addressing one of the major
bottlenecks facing this emerging and promising field.
For further information, please visit:
www.pcibiotech.com
Forward-looking
statements This
announcement may contain forward-looking statements, which as such
are not historical facts, but are based upon various assumptions,
many of which are based, in turn, upon further assumptions. These
assumptions are inherently subject to significant known and unknown
risks, uncertainties and other important factors. Such risks,
uncertainties, contingencies and other important factors could
cause actual events to differ materially from the expectations
expressed or implied in this announcement by such forward-looking
statements. PCI Biotech disclaims any obligation to update or
revise any forward-looking statements, whether as a result of new
information, future events or otherwise.
Pci Biotech Holding Asa (LSE:0JGL)
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