e-Therapeutics plc Filing of eight patent applications (3245U)
01 Agosto 2022 - 1:00AM
UK Regulatory
TIDMETX
RNS Number : 3245U
e-Therapeutics plc
01 August 2022
e-therapeutics plc
("e-therapeutics" or the "Company")
Filing of eight patent applications on
proprietary GalNAc-siRNA technology and target related
innovation
London, UK, 1 August 2022 - e-therapeutics plc (AIM: ETX; OTCQX;
ETXPF), a specialist in computational drug discovery with a focus
on developing RNA interference ("RNAi") therapeutics, today
announced the filing of eight further patent applications in the
United States ("US") to protect innovation arising from
e-therapeutics' proprietary GalNAc-siRNA technology.
The Company uses its proprietary GalNAc-siRNA technology to
silence any gene in liver hepatocytes. As announced on 26 October
2021, e-therapeutics' GalNAc-siRNA constructs have demonstrated
compelling in vivo performance in terms of depth of gene silencing
and duration of action.
The eight patent applications relate to innovation arising from
the Company's work on its pipeline of pre-clinical siRNA candidates
in several therapeutic areas and include innovation around novel
target ideas and associated disease-relevant biology identified
using the Company's computational platform, novel siRNA
therapeutics and novel siRNA chemistries associated with such siRNA
therapeutics.
This news follows e-therapeutics' announcement on 4 May 2022, as
part of its year-end results statement, that eleven patent
applications had been filed to protect proprietary and novel
GalNAc-siRNA silencing construct designs.
Ali Mortazavi, Chief Executive Officer of e-therapeutics,
commented:
"This second announcement of significant patent filings within
three months demonstrates fast and meaningful scientific and
technological progress. It also reflects our commitment to
protecting the Company's proprietary innovation, which forms a
critical part of our strategy as we continue to make material steps
in developing a computationally driven in-house pipeline of highly
differentiated RNAi medicines at speed. Our computational platform
not only affords us an important advantage in drug discovery, but
also in IP strategy, and we are leveraging this position in our
patent applications."
Enquiries:
e-therapeutics plc
Ali Mortazavi, CEO Tel: +44 (0)20 4551
James Chandler, VP IR & Communications 8888
www.etherapeutics.co.uk
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SP Angel Corporate Finance LLP
Tel: +44(0)20 3470 0470
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Nominated Adviser and Broker
--------------------------
Matthew Johnson/Caroline Rowe (Corporate
Finance)
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Vadim Alexandre/Rob Rees (Corporate Broking)
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About e-therapeutics plc
e-therapeutics plc is a UK-based company integrating
computational power and biological insight to accelerate the
discovery of life-transforming medicines. The Company has developed
and validated a powerful, disease- and modality-agnostic
computational approach to drug discovery, leveraging its
industry-leading expertise in network biology to capture and
interrogate human disease complexity more fully.
The Company's multi-disciplinary team builds computational
models of biological functions to transform the search for new
medicines, interventions, mechanisms and genetic support. Its
biology-led in silico laboratory enables rapid hypothesis
generation and screening. Novel targets can also be identified,
prioritised and assessed. Harnessing internal target gene
discoveries, e- therapeutics is currently building an in-house
pipeline of RNAi based medicines, using its proprietary
GalNAc-siRNA technology.
e-therapeutics has deployed and validated its computational drug
discovery platform both in house and with partners, including Novo
Nordisk, Galapagos NV, iTeos and a US-based, top 5 pharmaceutical
company.
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END
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