e-Therapeutics plc Filing of four patent applications (0686P)
07 Febrero 2023 - 01:00AM
UK Regulatory
TIDMETX
RNS Number : 0686P
e-Therapeutics plc
07 February 2023
e-therapeutics plc
("e-therapeutics" or the "Company")
Filing of four new patent applications on novel target
innovation and
new siRNA chemistries
London, UK, 07 February 2023 - e-therapeutics plc (AIM: ETX;
OTCQX; ETXPF), a company integrating computational power and
biological data to discover life-transforming RNAi medicines,
announces the filing of four new patent applications to protect
innovation around novel gene targets, associated disease relevant
biology as well as proprietary siRNA ('short interfering RNA')
stabilisation chemistries.
The four new patent applications add to a rapidly growing patent
portfolio reflecting the Company's continued intense rate of
innovation associated with developing a computationally driven
in-house pipeline of RNAi drug candidates across a range of
therapeutic areas. The new patent applications build on a n active
period of IP generation reported in 2022 where a series of patent
applications were filed to protect 13 inventions.
Ali Mortazavi, Chief Executive Officer of e-therapeutics,
commented:
"This latest announcement of patent filings reflects our
continued pace of innovation and progress towards an in-house
pipeline of first-in-class RNAi candidates derived from our
computational platform. We will continue to build on this progress,
maintain the momentum of invention and actively protect our
expanding intellectual property portfolio."
Enquiries:
e-therapeutics plc
Ali Mortazavi, CEO Tel: +44 (0)20 4551
James Chandler, VP IR & Communications 8888
www.etherapeutics.co.uk
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SP Angel Corporate Finance LLP Tel: +44(0)20 3470 0470
Nominated Adviser and Broker
Matthew Johnson/Harry Davies-Ball (Corporate
Finance)
Vadim Alexandre/Rob Rees (Corporate Broking)
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About e-therapeutics plc www.etherapeutics.co.uk
e-therapeutics plc ("ETX") integrates computational power and
biology information to discover life-transforming RNAi medicines.
The Company's technology uses computation to capture and model
human biology, identify novel targets, and develop RNAi medicines
against those targets that can be rapidly progressed to the
clinic.
ETX's proprietary Computational Biology Platform enables the
generation and analysis of biological network models, providing a
novel and mechanistic approach to drug discovery that explicitly
considers the true complexity of biology and makes more reliable
predictions from large complex data sets and ETX's proprietary
hepatocyte knowledgebase - the world's most comprehensive and
integrated hepatocyte-centric data and information resource. The
Company generates, prioritises and tests millions of hypotheses in
silico to identify better therapeutic targets with higher
confidence.
ETX's proprietary RNAi Platform enables the targeted delivery to
hepatocytes in the liver and the specific silencing of novel
disease-associated genes, identified by ETX's Computational Biology
Platform. The focus on hepatocytes offers the opportunity to work
across a wide variety of diseases. The liver is a highly
metabolically active organ which performs a key role in many
biological processes and vital functions crucial for human health.
ETX's GalNAc-siRNA constructs have demonstrated compelling in vivo
performance in terms of depth of gene silencing and duration of
action.
ETX is progressing a pipeline of first-in-class pre-clinical
RNAi candidates in several therapeutic areas including haematology,
cardiovascular disease and non-alcoholic steatohepatitis ("NASH").
ETX has also partnered with biopharma companies such as Novo
Nordisk, Galapagos NV and iTeos Therapeutics using its
computational network biology approach across a diverse range of
drug discovery projects.
The Company is based in London, UK and listed on the Alternative
Investment Market of the London Stock Exchange ("AIM"), with ticker
symbol ETX. e-therapeutics is also traded on the OTCQX Best Market
(OTCQX) in the United States, under ticker symbol ETXPF.
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