Poolbeg Pharma PLC POLB001 US Patent Update
07 Septiembre 2021 - 1:00AM
RNS Non-Regulatory
TIDMPOLB
Poolbeg Pharma PLC
07 September 2021
RNS REACH
Poolbeg Pharma plc
POLB 001 US Patent update
7 September 2021 - Poolbeg Pharma (AIM: POLB), 'Poolbeg' or the
'Company', a clinical stage infectious disease pharmaceutical
company with a capital light clinical model, provides an update on
the strengthening of its intellectual property (IP) position around
lead product, POLB 001, a small molecule immunomodulator for the
treatment of severe influenza.
As detailed in the Admission Document, Poolbeg has a worldwide
license for POLB 001 and is developing a strong IP portfolio with
patent protections in place covering the use of the class of p38
MAP kinase (mitogen-activated protein kinase) inhibitors for the
treatment or prevention of severe influenza and hypercytokinaemia
(or "cytokine storm"). The Company continues to also evaluate POLB
001's therapeutic uses beyond severe influenza.
The US Patent and Trademarks Office examiner reviewing the
patent application around POLB 001 has indicated to the Company
that the majority of the claims, including the main claim are
allowable. The main claim relates to the use of p38 MAP kinase
inhibitors as a class of compounds, including POLB 001, for the
treatment of severe influenza through modulation of the immune
response. Poolbeg anticipates receiving a formal patent grant in
due course.
The European patent was granted prior to the IPO with claims to
the treatment of severe influenza, which is characterised by
symptoms that persist or recur for more than two days without signs
of resolution, with a p38 MAP kinase inhibitor inhibiting the
release of pro-inflammatory mediators from endothelial cells and
pro-inflammatory cytokines from immune cells. This granted patent
offers protection until 2037.
Assessment of the applications filed in other territories is
ongoing.
Jeremy Skillington, PhD, CEO of Poolbeg Pharma said:
"Our US patent assessment is going to plan and we look forward
to updating our shareholders when we receive confirmation of its
grant. With the fast-growing infectious disease market expected to
exceed $250bn by 2025 and the current market for influenza already
c. $800m, the protection of our intellectual property is very
important. As stated in our AIM Admission Document upon listing,
our intention is to continue to aggressively file patent
applications to protect Poolbeg's assets."
- Ends -
Enquiries
Poolbeg Pharma Plc
Jeremy Skillington, CEO
Ian O'Connell, CFO +353 (0) 1 644 0007
finnCap Ltd (Nominated Adviser & Joint
Broker)
Geoff Nash, James Thompson, Charlie
Beeson +44 (0) 20 7220 0500
Arden Partners PLC (Joint Broker)
John Llewellyn-Lloyd, Louisa Waddell,
Oscair McGrath +44 (0) 207 614 5900
J&E Davy (Joint Broker)
Anthony Farrell, Niall Gilchrist +353 (0) 1 679 6363
Instinctif Partners +44 (0) 20 7457 2020
Melanie Toyne Sewell, Rozi Morris, Tim poolbeg@instinctif.com
Field
About Poolbeg Pharma
Poolbeg Pharma is a clinical stage infectious disease
pharmaceutical company, with a capital light clinical model which
aims to develop multiple products faster and more cost effectively
than the conventional biotech model. The Company, headquartered in
London, is led by a team with a track record of creation and
delivery of shareholder value and aspires to become a "one-stop
shop" for Big Pharma seeking mid-stage products to licence or
acquire.
The Company is targeting the growing infectious disease market.
In the wake of the COVID-19 pandemic, infectious disease has become
one of the fastest growing pharma markets and is expected to exceed
$250bn by 2025.
With its initial assets from Open Orphan plc, an industry
leading infectious disease and human challenge trials business,
Poolbeg has access to knowledge, experience, and clinical data from
over 20 years of human challenge trials. The Company is using these
insights to acquire new assets as well as reposition clinical stage
products, reducing spend and risk. It already has a Phase II ready
repositioned small molecule immunomodulator for severe influenza
and a portfolio of other exciting assets. The Company plans to
broaden this portfolio further going forward and is in active
discussions with AI data analysis platforms to help accelerate the
power of its human challenge model data and biobank.
For more information, please go to www.poolbegpharma.com
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