FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

JOHNSON RADY A
2. Issuer Name and Ticker or Trading Symbol

PFIZER INC [ PFE ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
Executive Vice President
(Last)          (First)          (Middle)

PFIZER INC.-CORP. SECRETARY, 235 EAST 42ND ST.
3. Date of Earliest Transaction (MM/DD/YYYY)

12/3/2021
(Street)

NEW YORK, NY 10017
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 12/3/2021  S  200.0000 D$53.4700 74644.0000 D  
Common Stock 12/3/2021  S  300.0000 D$53.5100 74344.0000 D  
Common Stock 12/3/2021  S  371.0000 D$53.3700 73973.0000 D  
Common Stock 12/3/2021  S  400.0000 D$53.4100 73573.0000 D  
Common Stock 12/3/2021  S  500.0000 D$53.4200 73073.0000 D  
Common Stock 12/3/2021  S  1200.0000 D$53.4900 71873.0000 D  
Common Stock 12/3/2021  S  2200.0000 D$53.4600 69673.0000 D  
Common Stock 12/3/2021  S  2719.0000 D$53.5000 66954.0000 D  
Common Stock 12/3/2021  S  2756.0000 D$53.4000 64198.0000 D  
Common Stock 12/3/2021  S  3627.0000 D$53.3800 60571.0000 D  
Common Stock 12/3/2021  S  4727.0000 D$53.3900 55844.0000 D  
Common Stock         5714.0000 I By Rule 16b-3 Plan 

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares

Explanation of Responses:

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
JOHNSON RADY A
PFIZER INC.-CORP. SECRETARY
235 EAST 42ND ST.
NEW YORK, NY 10017


Executive Vice President

Signatures
Susan E. Grant, by power of atty., for Rady A. Johnson12/6/2021
**Signature of Reporting PersonDate

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