RNS Number:1240Q
Alizyme PLC
24 September 2003


Immediate Release                                            24 September 2003


                                  ALIZYME PLC

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


Cambridge, UK, 24 September 2003: Alizyme plc (London Stock Exchange: AZM)
announces that it received, yesterday, the following notification under
Companies Act 1985 ss.198-202 (as amended), from Hg Pooled Management Limited.


"Companies Act 1985 ss. 198-202
Disclosure Of Interests In Shares

Pursuant to the above provisions we hereby notify you on behalf of our client of
the following change of interest in shares of your Company.

As at 23rd September 2003 the interest is as follows:

Name of Client:                                    HGT L.P.

Class of Shares:                                   Ordinary

Holding:                                           3,868,775

Level of Interest:                                 2.8%

For further information, please contact:

Mr Tim McCarthy, Finance Director
ALIZYME plc                                         Tel No: + 44 (0)1223 896000

Lisa Baderoon
BUCHANAN COMMUNICATIONS                            Tel No: + 44 (0)20 7466 5000

Further information on Alizyme can be found on the Company's website:
www.alizyme.com

                      This information is provided by RNS
            The company news service from the London Stock Exchange

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