via NEWMEDIAWIRE -- CFN Media Group (“CFN Media”), the leading
agency and financial media network dedicated to the North American
cannabis industry, announces the publication of an article covering
biosynthesis and International Cannabis Corp.’s recent
biotechnology investment.
Biosynthesis is the process of manipulating simple substances to
produce the complex molecules found within living organisms.
Biosynthetic engineering, as applied to cannabis, means single cell
organisms are programmed to synthesize the enzymes for the
metabolic pathway that generates cannabinoids from sugars -
promising new technology with the potential to shake up the nascent
cannabis industry.
Guided by an understanding of the potential the technology
offers, International Cannabis Corp. (CSE: WRLD.U)(FWB:
8K51)(OTC: WLDCF) announced on April 8th a USD $1.2 million
strategic investment in Biotii Technologies Corp. a
leading private biotechnology company actively pursuing genetically
engineered microorganisms that express cannabinoid profiles
identical to those found in nature - at a fraction of the cost of
current production methods with more consistent quality and a
greatly reduced carbon footprint.
Revolutionary Potential
Recent advancements in the areas of gene editing, in-silico
protein modeling, and semi-automated high throughput robotics has
enabled Biotii to expedite its molecular biology research, allowing
the company to spearhead into large-scale production with a wide
portfolio of intellectual property. This evolving portfolio is
expected to consist of synthetic cannabinoids, designer enzymes,
proprietary enzyme pathways, and GMO microorganisms.
Traditional cultivation of cannabis plants for the purpose of
extracting cannabidiolic acid (CBDA), THC and CBD is a time,
labour, and resource intensive endeavor which often results in
lower yields. By 2020, the Biotii team plans to establish processes
to mass-produce CBD/THC in quantities of hundreds of metric tons
per annum boasting stable and consistent yields, pharmaceutical
grade purities, and the lowest production costs in the cannabis
space.
Commenting on the investment, Eugene Beukman, Chief Executive
Officer and a Director of International Cannabis, said, “We are
thoroughly impressed with the Biotii team, which consists of proven
innovators from world-class institutions, whom we believe are en
route to potentially disrupt a very large part of the cannabis
value chain. ICC will continue to support Biotii’s distinguished
team in their pursuit to bring economies of scale using
biosynthesis to the cannabis industry. This investment enhances
ICC’s ability to capture significant IP and market share in the
fast-developing biosynthesis market for cannabinoids.”
In areas with more established cannabis markets, extract-based
products have proven to be just as popular, and often more so, than
the smoking of flower. Most consumers are new to cannabis and
increasingly health conscious, so they’re much more likely to
purchase derivatives and consumables. The development of
biosynthetic cannabinoids could potentially eliminate the need for
companies producing these products to invest in cultivation and
processing, substantially lowering input costs and increasing
revenues, while also cutting the industry’s overall ecological
footprint.
Industry Investment Enabling Research
ICC’s investment in biosynthesis mirrors those made
by Cronos and Tilray in September of last
year.
Cronos is working with synthetic biology firm Ginkgo Bioworks in
an effort to develop a scalable system for producing synthetic
cannabinoids, and if certain benchmarks are achieved, the deal
could be worth USD $100 million in cash and stock incentives. This
would give Cronos the exclusive right to commercialize key patented
intellectual property related to the target cannabinoids in
perpetuity. These include THC and CBD, but also lesser-known
compounds also produced by the cannabis plant, which are of
particular importance to pharmaceutical companies.
Tilray is working with IntelGenX Corp. to develop oral film
products infused with synthetic cannabis for both recreational and
medicinal use, citing a need for the greater consistency synthetics
offer, especially for medical cannabis patients, as well as being
free of the contaminants sometimes present in naturally-sourced
cannabinoids.
The US Food & Drug Administration has been slow to approve
synthetic cannabinoids, but since 2016, has started to liberalize
its approach, a key step in advancing research.
ICC’s strategic investment with Biotii grants International
Cannabis a right of first refusal with respect to all future Biotii
financing.
Biotii Guided by a Winning Team
Dr. John Harrold, Biotii’s Chief Executive Officer, said,
“Biotii looks forward to progressing our technology alongside ICC
and their robust cannabis platform. ICC has earned a reputation of
being a thought leader in the space and we are excited by the
possibilities of tapping into ICC’s unique expertise and resources
as we look to disrupt the cannabis industry.”
Dr. Harrold is an MIT instructor with expertise in end-to-end
bio-lab management, and a proven entrepreneur, having previously
championed four start-ups, including two funded by the National
Science Foundation. Biotii has forged mission critical
relationships with leading medical research institutions in both
the United States and China.
Sisi Ni, Biotii’s Chief Product Officer, is an MIT trained
materials scientist and engineer who was previously named as one of
Forbes’ 30 under 30. Casey Solomon, PhD, the company’s Chief
Science Officer/Lead Scientist, is a resident expert in yeast
engineering, E. coli engineering, and molecular pathway
engineering. Biotii’s Chief Medical Officer is Ryan Hubbard, MD, a
former instructor at Mayo Clinic Graduate School of Medicine with
over 25 publications, posters, and oral presentations.
Nona Tian, PhD is the company’s Science Advisor/Affiliated
Researcher, a Xiamen University PhD graduate in Cell and Molecular
Biology with a B.S. in biotechnology as well as a successful
startup co-founder with extensive bioengineering experience. Peter
Liu, Biotii’s Technology Advisor/Affiliated Researcher also
graduated from Xiamen University with a B.S. in biotechnology, and
is a seasoned protein engineer and startup co-founder that received
various grants from the Chinese Government for bioengineering
initiatives.
If the biosynthesis of cannabinoids proves to be a scalable
technology, many of the companies involved in the production and
sale of extract-based products could switch from traditional
cultivation and processing to achieve their supplies in this
alternative form, which would leave those with the foresight to
invest in the technology now in a position to capitalize. Investors
would do well to keep an eye on biosynthesis research and the
companies like ICC who are making important moves now.
For more information, watch this page or
visit https://intlcannabiscorp.com/news/
Please follow the link to read the full
article: https://www.cannabisfn.com/icc-makes-strategic-investment-in-disruptive-biosynthesis-research/
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