RNS Number:5760K
Bioscience Inv Trust PLC
04 April 2005

FOR IMMEDIATE RELEASE                                          04-April-05

To : The London Stock Exchange

The Bioscience Investment Trust plc

The Board of the The Bioscience Investment Trust plc announces that the top ten
holdings as at Thursday 31st March 2005 are:-

Amgen                                    4.65%

Gilead Sciences                          4.29%

Celgene Corporation                      3.40%

Shire Pharmaceuticals                    3.27%

Paion GMBH                               2.92%

Gen-Probe                                2.89%

United Therapeutics                      2.85%

Acambis                                  2.47%

MGI Pharma                               2.15%

Gyrus                                    1.95%



By Order of the Board


Schroder Investment Management Limited



Secretaries





The Bioscience Investment Trust Fund plc







Enquiries :
                           Anthony Carney 020 7658 2548





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