Quester VCT 4 plc                               

           Interim statement for the six months ended 30 April 2006            

Financial highlights

Per ordinary share (pence)                  30 April    31 October     30 April
                                                2006          2005         2005    
                             
Capital values                                                                 
                                                                               
Net asset value                                 65.2          61.3         64.4
                                                                               
Share price                                     54.0          60.0         60.0
                                                                               
Return and dividends                                                           
                                                                               
Dividend                                         1.0*          1.0          1.0
                                                                               
Cumulative dividend                              4.9           3.9          3.9
                                                                               
Total return**                                  70.1          65.2         68.3
                                                                               
*The 2006 interim dividend was paid on 1 March 2006                            
                                                                               
** Net asset value plus cumulative dividend per share                          


An investment in Quester VCT 4 plc should be viewed as a high risk, long term
venture capital investment. Shareholders are reminded that a sale of their
shareholding in Quester VCT 4 plc may give rise to a loss of any capital gains
tax deferral granted at the time of their original subscription.

Interim Report

Overview

The Company's net asset value has risen by 3.9p per share to 65.2p over the six
months to 30 April 2006. Total return to shareholders, which takes account of
the interim dividend of 1p per share paid on 1 March 2006, has risen by 4.9p or
7.5% over the same period.

The portfolio has performed much as expected. Net asset value growth achieved
over the period has lagged that seen on the financial markets, which rose
strongly during the period. As the Company's investments are largely unquoted,
net asset value will not generally move in line with quoted markets. However,
during the period increasing business confidence produced a beneficial
environment for many of the companies in which we have invested, which has
helped them develop and grow.

Net assets and dividends

The movement in net assets is summarised in the table below:

                                                     �'000      Pence per
                                                                    share
                                                                         
Net asset value at 31 October 2005                  30,992           61.3
                                                                         
Income                                                 194            0.4
                                                                         
Operating expenses                                   (616)          (1.2)
                                                                         
Net realised gain on investments                     2,083            4.1
                                                                         
Net unrealised gain on investments                     753            1.5
                                                                         
Dividend paid, net of amounts reinvested             (476)          (1.0)
                                                                         
Share buy-backs                                      (496)            0.1
                                                                         
Net asset value at 30 April 2006                    32,434           65.2

The most significant event during the period was the cash sale of Footfall
Limited in December 2005, which gave rise to a realised gain of �2million,
equivalent to 4p per share. An interim dividend of 1p per share was declared on
the back of this successful exit. Net assets have also benefited from a net
upwards revaluation of investments of �753,000, or 1.5p per share. Further
information is provided on page 4. The directors do not propose a further
interim dividend.

Venture capital portfolio: realised gains and new investments

During the period, two investments were sold generating proceeds of �3.1million
and �3million was committed to new and follow-on investments.

In addition to the disposal of Footfall Limited, the residual holding of
Loudeye Inc, was sold. The Loudeye investment, which arose from the original
investment in On Demand Distribution Limited, returned an overall profit of �
221,000 on an original cost of �568,000.

This has been an active period in terms of further investment with funds being
committed to five companies new to the portfolio and 11 existing portfolio
investments.

The five new investments are:

                                                                          �'000
                                                                               
Cluster Seven Limited             Software                                  158
                                                                               
Haemostatix Limited               Biotechnology                               5
                                                                               
Lectus Therapeutics Limited       Biotechnology                              53
                                                                               
PanOpSys Limited                  Diagnostics & devices                      56
                                                                               
Perpetuum Limited                 Electronics                                93
                                                                               
                                                                            365

Other than the investment in Cluster Seven, which is revenue generating, these
investments are all early stage and pre-revenue. The initial investments are
deliberately small and further investment is to be made on an agreed milestone
related basis, the objective being to manage the Company's exposure to these
exciting but early stage, and therefore higher risk, investments.

Cluster Seven develops and sells enterprise spreadsheet management software.
The company's products provide control over spreadsheets being used in mission
critical environments. In the current regulatory environment, the control of
spreadsheets is paramount and there is a substantial potential global market
for Cluster Seven's products. The company has built an impressive client base,
principally in the major financial centres of London and New York.

Haemostatix is a drug discovery company concentrating on the development of an
alternative to blood platelet transfusion. The company's product, HaemoPlax(tm),
represents a new type of treatment that is potentially safer and easier to use
than the current therapy, with a significant saving in ancillary treatments
costs. This was a small initial investment; subsequent to 30 April, Quester VCT
4 together with the investment syndicate provided further planned funding to
Haemostatix, which had successfully achieved its initial scientific milestones.

Lectus Therapeutics specialises in the discovery and development of novel drugs
(ion channel modulators) for diseases associated with pain management, urinary
incontinence and angina, offering important clinical and economic advantages
over existing therapies in this growing market. The company raised �8.2million
in its first institutional round of venture capital funding (Series A) which
Quester co-led alongside a leading French venture capital firm, Sofinnova, and
the two largest Japanese pharmaceutical firms, Takeda and Astellas.

PanOpSys is a medical diagnostics company focusing on the provision of fast,
simple point-of-care diagnostics. Early diagnosis converts into substantial
savings for healthcare providers and point-of-care testing is the fastest
growing market sector in diagnostics. The company recently raised �3million in
a Series A funding led by Quester and is at an exciting stage in the
optimisation and commercialisation of its patented piezofilm technology.

Perpetuum produces electromechanical vibration energy harvesting
micro-generators to power wireless sensor nodes, eliminating the need for hard
wiring or batteries. This technology addresses the growing and substantial
market for wireless sensor systems, which are used for a wide range of
applications.

The majority of these new investments are shared with Quester's institutional
fund, the Quester Venture Partnership. Several have also been seed funded by
the Quester managed university linked funds, as part of Quester's proactive
deal sourcing strategy.

The Board has decided that no new companies should be added to the venture
capital portfolio for the time being. This reflects the existing diversity of
the venture capital portfolio of 38 investments and the fact that the Company's
remaining liquid assets are currently scheduled to provide further funding to
this portfolio. This situation will be kept under regular review and is likely
to change, particularly when cash proceeds are received on the future disposal
of investments.

�2.6million was invested as part of the planned further funding of 11 existing
companies in the portfolio, as below:

                                                                          �'000
                                                                               
Advanced Valve Technologies Limited   Industrial products & services        258
                                                                               
Identum Limited                       Software                              714
                                                                               
Azea Networks, Inc.                   Communications                        376
                                                                               
Celona Technologies Limited           Software                              357
                                                                               
Nomad Software Limited                Software                              190
                                                                               
Teraview Limited                      Diagnostics & devices                 197
                                                                               
Workshare Limited                     Software                              393
                                                                               
Others                                -                                     132
                                                                               
                                                                          2,617

Venture capital portfolio: valuation changes

Overall, the value of the venture capital portfolio has fallen over the period
by �324,000.

The largest individual valuation gain was seen on the now quoted investment in
Cyclacel Pharmaceuticals, Inc.. This company was formed on the merger of
Cyclacel Limited with Xcyte Therapies, Inc. to form a larger international
biopharmaceutical company with a franchise in one of the most exciting fields
of biology and with a development-stage portfolio of targeted oncology drug
candidates affecting the cancer cell cycle. The investment is now valued at its
market price, which has resulted in an uplift in its carrying value of �
149,000.

The quoted investment in Public Recruitment Group plc fell in value by �162,000
in autumn 2005 although recent news flow has, however, been more positive.

Avidex Limited, an Oxford based biotechnology company, secured further funding
via a significant investment from a new trade partner, Syngenta. This funding
will take the company through to the next stage of its development and
demonstrates the progress made with its science, although the fair value of the
investment has been reduced by �290,000 to reflect the pricing of this third
party investment. This valuation change reflects current valuation trends
across the biotechnology sector generally, as opposed to specific performance
issues with the business itself.

The valuation of the investment in Teraview was reduced by �108,000 back to
cost based on the pricing of the last round of equity financing.

Listed equity portfolio

The listed equity portfolio, which was showing an unrealised profit of �
1,877,000 as at 30 April 2006, has performed well and has generated a total
return over the six months of �1,172,000.

Outlook

Progress has been made by the portfolio and we were pleased with the profit
generated from the sale of Footfall, which serves to demonstrate the ability of
companies in the portfolio to deliver good returns. We believe that this
potential value will become increasingly apparent as the portfolio matures.

12 July 2006

Fund summary

as at 30 April 2006

                             Industry Sector  Original Valuation Equity %   % of  
                                                  Cost     �'000     held   fund  
                                                 �'000                      by    
                                                                            value 
                                                                                
Quoted venture capital                                                          
investments                                                                     
                                                                                
Allergy Therapeutics plc     Biotechnology         500       784     1.1%   2.4%  
                                                                                
Celoxica Holdings plc        Software            1,315       716     3.7%   2.2%  
                                                                                
Cyclacel Pharmaceuticals,    Biotechnology       1,000       399     0.5%   1.2%  
Inc.                                                                            
                                                                                
Genosis plc                  Diagnostics &         111        73     0.9%   0.2%  
                             devices                                            
                                                                                
Polaron plc                  Industrial            250       110     1.2%   0.3%  
                             products &                                         
                             services                                           
                                                                                
Portrait Software plc        Software            1,130       379     5.0%   1.2%  
                                                                                
Public Recruitment Group plc Industrial            250        51     0.8%   0.2%  
                             products &                                         
                             services                                           
                                                                                
Quadnetics Group plc         Electronics           143       127     0.5%   0.4%  
                                                                                
Total quoted venture capital                     4,699     2,639            8.1%  
investments                                                                     
                                                                                
Unquoted venture capital                                                        
investments                                                                     
                                                                                
Advanced Valve Technologies  Industrial          1,730     1,032    30.6%   3.2%  
Limited                      Products &                                         
                             Services                                           
                                                                                
Antenova Limited             Communications      1,254     1,005     5.4%   3.1%  
                                                                                
Anthropics Technology        Communications         95        25     7.0%   0.1%  
Limited                                                                         
                                                                                
Arithmatica Limited          Semiconductors        429       429    13.7%   1.3%  
                                                                                
Avidex Limited               Biotechnology       1,144       525     2.6%   1.6%  
                                                                                
Azea Networks, Inc.          Communications      2,140     2,140     7.9%   6.6%  
                                                                                
Celona Technologies Limited  Software            1,023     1,023    13.6%   3.2%  
                                                                                
Cluster Seven Limited        Software              158       158     2.0%   0.5%  
                                                                                
De Novo Pharmaceuticals      Diagnostics &         803       176     3.0%   0.5%  
Limited                      devices                                            
                                                                                
Elateral Holdings Limited    Software              655       155    13.7%   0.5%  
                                                                                
Global Silicon Limited       Semiconductors         67        67     0.8%   0.2%  
                                                                                
Haemostatix Limited          Biotechnology           5         5     0.6%   0.0%  
                                                                                
HTC Healthcare Group plc     Consumer              714       425     8.7%   1.3%  
                             services                                           
                                                                                
Identum Limited              Software              980       980    13.7%   3.0%  
                                                                                
Lectus Therapeutics Limited  Biotechnology          53        53     1.5%   0.1%  
                                                                                
Level Four Software Limited  Software               68        68     0.7%   0.2%  
                                                                                
Lorantis Holdings Limited    Biotechnology       1,400     1,025     2.7%   3.2%  
                                                                                
Mesophotonics Limited        Electronics           893       670     7.4%   2.1%  
                                                                                
Nexagent Limited             Software            1,537     1,458     5.8%   4.5%  
                                                                                
Nomad Software Limited       Software            1,402       832     7.5%   2.6%  
                                                                                
Opsys Management Limited     Electronics           288        72     3.5%   0.2%  
                                                                                
Oxford Immunotec Limited     Diagnostics &       1,339     1,556     9.3%   4.8%  
                             devices                                            
                                                                                
Oxxon Therapeutics Holdings, Biotechnology         985       492     3.5%   1.5%  
Inc.                                                                            
                                                                                
PanOpSys Limited             Diagnostics &          56        56     2.1%   0.2%  
                             devices                                            
                                                                                
Pelikon Limited              Hardware               69        69     0.5%   0.2%  
                                                                                
Perpetuum Limited            Electronics            93        93     1.7%   0.3%  
                                                                                
Sift Group Limited           Internet              917       698     6.2%   2.2%  
                                                                                
TeraView Limited             Diagnostics &         947       947     5.4%   2.9%  
                             devices                                            
                                                                                
Workshare Limited            Software            1,532     1,632     6.8%   5.0%  
                                                                                
Xention Discovery Limited    Biotechnology         750       825     5.1%   2.5%  
                                                                                
Total unquoted venture                          23,526    18,691           57.6% 
capital investments                                                             
                                                                                
Total venture capital                           28,225    21,330           65.7% 
investments                                                                     
                                                                                
Listed equity investments                        5,092     6,969           21.5% 
                                                                                
Total investments                               33,317    28,299           87.2% 
                                                                                
Cash and other net assets                        4,135     4,135           12.8% 
                                                                                
Net assets                                      37,452    32,434          100.0%

Unaudited financial statements

Profit and loss account

                                     Note    6 months     6 months   Year ended
                                             ended 30     ended 30   31 October
                                           April 2006   April 2005        2005 
                                          Total �'000  Total �'000   Total �'000
                                                                               
Net gains/(losses) on fair value                2,836        (811)      (2,141)
through profit or loss on                                                      
investments                                                                    
                                                                               
Income                                            194          211          437
                                                                               
Investment management fee                       (398)        (429)        (847)                                                             
                 
Other expenses                                  (215)        (188)        (324)
                                                                               
Profit/(loss) on operating                      2,417      (1,217)      (2,875)
activities                                                                     
                                                                               
Interest payable on loan notes                    (3)          (3)          (5)
                                                                               
Profit/(loss) on ordinary                       2,414      (1,220)      (2,880)
activities before taxation                                                     
                                                                               
Tax on ordinary activities                          -            -            -
                                                                               
Profit/(loss) on ordinary                       2,414      (1,220)      (2,880)
activities after taxation                                                      
                                                                               
Basic and diluted profit/(loss)         3        4.8p       (2.4)p       (5.6)p
per share                                                                      

Statement of historical cost profits and losses

                                             6 months     6 months   Year ended
                                             ended 30     ended 30   31 October
                                           April 2006   April 2005         2005
                                                �'000        �'000        �'000
                                                                               
Profit/(loss) on ordinary activities            2,414      (1,220)      (2,880)
before taxation                                                                
                                                                               
Realisation of prior years' net                   120      (4,010)      (3,722)
unrealised gains/(losses) on investments                                       
                                                                               
Historical cost profit/(loss) on                2,534      (5,230)      (6,602)
ordinary activities before taxation                                            
                                                                               
Historical cost profit/(loss) for the           2,534      (5,230)      (6,602)
period                                                                         

All items in the above statement derive from continuing operations.

The Company has only one class of business and derives its income from
investments made in shares and securities and from bank deposits.

Balance sheet
                                           Note  30 April 31 October  30 April
                                                     2006       2005      2005 
                                                    �'000      �'000     �'000    
                                                            
Fixed assets                                                                   
                                                                               
Investments                                         28,299    25,474     25,301
                                                                               
Current assets                                                                 
                                                                               
Debtors                                                183       337        362
                                                                               
Cash at bank                                         4,382     5,641      7,943
                                                                               
                                                     4,565     5,978      8,305
                                                                               
Creditors (amounts falling due within one            (330)     (360)      (402)
year)                                                                          
                                                                               
Net current assets                                   4,235     5,618      7,903
                                                                               
Creditors (amounts falling due in over one           (100)     (100)      (100)
year)                                                                          
                                                                               
Net assets                                          32,434    30,992     33,104
                                                                               
Share capital and reserves                                                     
                                                                               
Called-up equity share capital                         497       506        514
                                                                               
Capital redemption reserve                              35        26          -
                                                                               
Share premium account                                  310       285        284
                                                                               
Special reserve                                     34,437    34,969     35,820
                                                                               
Fair value reserve                                 (5,019)   (5,652)    (3,983)
                                                                               
Profit and loss account                              2,174       858        469
                                                                               
Total equity shareholders' funds                    32,434    30,992     33,104
                                                                               
Net asset value per share                            65.2p     61.3p      64.4p

Summarised cash flow statement

                                      6 months       6 months        Year ended
                                      ended 30       ended 30        31 October
                                      April 2006     April 2005            2005
                                      �'000          �'000                �'000
                                                                               
Cash outflow from operating           (260)          (147)                (494)
activities                                                                     
                                                                               
Net capital expenditure and financial (27)           (179)              (1,682)
investment                                                                     
                                                                               
Equity dividends paid                 (501)          (521)                (521)
                                                                               
Buy-back of ordinary shares           (496)          (463)                (915)
                                                                               
Issue of shares under the dividend    25             68                      68
reinvestment scheme                                                            
                                                                               
Decrease in cash for the period       (1,259)        (1,242)            (3,544)
                                                                               
Reconciliation of net cash flow to                                             
movement in net funds                                                          
                                                                               
Decrease in cash for the period       (1,259)        (1,242)            (3,544)
                                                                               
Net cash at the start of the period   5,641          9,185                9,185
                                                                               
Net cash at the end of the period     4,382          7,943                5,641

Reconciliation of movement in shareholders' funds

                                Share    Capital   Share Special    Fair   Profit
                              capital redemption premium reserve   value and loss
                                         reserve account         reserve  account   
                                �'000      �'000   �'000   �'000   �'000    �'000
                                                                                                                        
At 1 November 2005                506         26     285  34,969 (5,652)     858
                                                                                
Shares purchased for              (9)          9       -   (496)       -       -
cancellation                                                                    
                                                                                
Shares issued under the terms       -          -      25       -       -       -
of the dividend reinvestment                                                    
scheme                                                                          
                                                                                
Transfer of net unrealised          -          -       -       -     753   (753)
gain on revaluation of                                                          
investments to fair value                                                       
reserve                                                                         
                                                                                
Realisation of prior years'         -          -       -       -   (120)     120
net unrealised gains on                                                         
investments                                                                     
                                                                                
Transfer from special reserve       -          -       -    (36)       -      36
to profit and loss account                                                      
                                                                                
Dividends paid (note 2)             -          -       -       -       -   (501)
                                                                                
Profit on ordinary activities       -          -       -       -       -   2,414
after taxation                                                                  
                                                                                
At 30 April 2006                  497         35     310  34,437 (5,019)   2,174

Notes to the unaudited financial statements

1. This Interim Report has been prepared using new accounting standards, which
have been issued to begin the process of converging UK standards with
International Financial Reporting Standards ("IFRS"). The relevant standards
are FRS 25 Financial Instruments: Disclosure and Presentation and FRS 26
Financial instruments: Measurement. These standards have been adopted by the
Company with effect from 1 November 2005.

Listed investments actively traded in organised financial markets are valued at
fair value which is generally determined by reference to Stock Exchange quoted
market bid prices at the close of business on the balance sheet date.
Previously all listed investments were valued with reference to closing
mid-market prices at the balance sheet date. The effect of this change in
accounting policy on the net asset value of the Company as at 30 April 2006 has
been to reduce it by �51,000. The comparative figures have not been restated as
the impact is immaterial.

In addition, transaction costs incurred on the purchase and sale of investments
are now charged through the Profit and Loss Account in the period in which they
are incurred instead of being included within the cost of the investment or
deducted from the proceeds of a sale. The effect of this change in accounting
policy has been to decrease profit on ordinary activities after tax by �6,900
although the overall impact is net asset value neutral. The comparative figures
have not been restated as the impact is immaterial.

2. On 10 January 2006 the directors resolved to pay an interim dividend of 1p
per share. This was paid on 1 March 2006.

3. The calculation of the profit per share for the period is based on the net
profit after taxation of �2,414,000 divided by the weighted average number of
shares in issue during the period of 50,341,560.

4. The unaudited financial statements set out above do not constitute statutory
accounts within the meaning of Section 240 of the Companies Act 1985.

5. Copies of the unaudited interim results are expected to be sent to
shareholders on 13 July 2006. Further copies can be obtained from the Company's
registered office.

A copy of the above document is to be submitted to the UK Listing Authority,
and will shortly be available for inspection at the UK Listing Authority's
Document Viewing Facility, which is situated at:

Financial Services Authority

25 The North Colonnade

Canary Wharf

London E14 5HS



END

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