TIDMSHP 
 
   BLOCK LISTING SIX MONTHLY RETURN 
 
   November 23, 2018 - Shire plc (LSE: SHP, NASDAQ: SHPG) 
 
 
 
 
Name of applicant:                                              Shire plc 
--------------------------------------------------------------  -------------------------------- 
Name of scheme:                                                 Shire Sharesave Scheme 
--------------------------------------------------------------  -------------------------------- 
                                                                                   November 22, 
Period of return:                     From:                     May 23, 2018  To:  2018 
------------------------------------  ------------------------  ------------  ---  ------------- 
Balance of unallotted securities under scheme(s) from 
 previous return:                                                                        159,388 
--------------------------------------------------------------  -------------------------------- 
Plus: The amount by which the block scheme(s) has 
 been increased since the date of the last return (if 
 any increase has been applied for):                                                         Nil 
--------------------------------------------------------------  -------------------------------- 
Less: Number of securities issued/allotted under scheme(s) 
 during period (see LR3.5.7G):                                                               Nil 
--------------------------------------------------------------  -------------------------------- 
Equals: Balance under scheme(s) not yet issued/allotted 
 at end of period:                                                                       159,388 
--------------------------------------------------------------  -------------------------------- 
 
 
 
 
 
 
Name of applicant:                                              Shire plc 
--------------------------------------------------------------  -------------------------------- 
Name of scheme:                                                 Shire Portfolio Share Plan 
--------------------------------------------------------------  -------------------------------- 
                                                                                   November 22, 
Period of return:                     From:                     May 23, 2018  To:  2018 
------------------------------------  ------------------------  ------------  ---  ------------- 
Balance of unallotted securities under scheme(s) from 
 previous return:                                                                        168,594 
--------------------------------------------------------------  -------------------------------- 
Plus: The amount by which the block scheme(s) has 
 been increased since the date of the last return (if 
 any increase has been applied for):                                                         Nil 
--------------------------------------------------------------  -------------------------------- 
Less: Number of securities issued/allotted under scheme(s) 
 during period (see LR3.5.7G):                                                            25,472 
--------------------------------------------------------------  -------------------------------- 
Equals: Balance under scheme(s) not yet issued/allotted 
 at end of period:                                                                       143,122 
--------------------------------------------------------------  -------------------------------- 
 
 
 
 
 
 
 
 
 
Name of applicant:                                              Shire plc 
--------------------------------------------------------------  -------------------------------- 
                                                                Shire Employee Stock Purchase 
Name of scheme:                                                 Plan 
--------------------------------------------------------------  -------------------------------- 
                                                                                    November 22, 
Period of return:                     From:                     May 23, 2018   To:  2018 
------------------------------------  ------------------------  -------------  ---  ------------ 
Balance of unallotted securities under scheme(s) from 
 previous return:                                                                        237,698 
--------------------------------------------------------------  -------------------------------- 
Plus: The amount by which the block scheme(s) has 
 been increased since the date of the last return (if 
 any increase has been applied for):                                                         Nil 
--------------------------------------------------------------  -------------------------------- 
Less: Number of securities issued/allotted under scheme(s) 
 during period (see LR3.5.7G):                                                               Nil 
--------------------------------------------------------------  -------------------------------- 
Equals: Balance under scheme(s) not yet issued/allotted 
 at end of period:                                                                       237,698 
--------------------------------------------------------------  -------------------------------- 
 
 
 
 
 
 
Name of applicant:                                              Shire plc 
--------------------------------------------------------------  -------------------------------- 
                                                                Shire Long Term Incentive Plan 
Name of scheme:                                                 2015 
--------------------------------------------------------------  -------------------------------- 
                                                                                    November 22, 
Period of return:                     From:                     May 23, 2018   To:  2018 
------------------------------------  ------------------------  -------------  ---  ------------ 
Balance of unallotted securities under scheme(s) from 
 previous return:                                                                      1,860,982 
--------------------------------------------------------------  -------------------------------- 
Plus: The amount by which the block scheme(s) has 
 been increased since the date of the last return (if 
 any increase has been applied for):                                                         Nil 
--------------------------------------------------------------  -------------------------------- 
Less: Number of securities issued/allotted under scheme(s) 
 during period (see LR3.5.7G):                                                            31,044 
--------------------------------------------------------------  -------------------------------- 
Equals: Balance under scheme(s) not yet issued/allotted 
 at end of period:                                                                     1,829,938 
--------------------------------------------------------------  -------------------------------- 
 
 
 
 
 
 
Name of applicant:                                              Shire plc 
--------------------------------------------------------------  -------------------------------- 
                                                                Shire Global Employee Stock 
Name of scheme:                                                 Purchase Plan 
--------------------------------------------------------------  -------------------------------- 
                                                                                    November 22, 
Period of return:                     From:                     May 23, 2018  To:   2018 
------------------------------------  ------------------------  ------------  ----  ------------ 
Balance of unallotted securities under scheme(s) from 
 previous return:                                                                        800,445 
--------------------------------------------------------------  -------------------------------- 
Plus: The amount by which the block scheme(s) has 
 been increased since the date of the last return (if 
 any increase has been applied for):                                                         Nil 
--------------------------------------------------------------  -------------------------------- 
Less: Number of securities issued/allotted under scheme(s) 
 during period (see LR3.5.7G):                                                           613,935 
--------------------------------------------------------------  -------------------------------- 
Equals: Balance under scheme(s) not yet issued/allotted 
 at end of period:                                                                       186,510 
--------------------------------------------------------------  -------------------------------- 
 
 
 
 
 
 
Name of applicant:                                              Shire plc 
--------------------------------------------------------------  -------------------------------- 
Name of scheme:                                                 Baxalta Exchange Awards 
--------------------------------------------------------------  -------------------------------- 
                                                                                   November 22, 
Period of return:                     From:                     May 23, 2018  To:  2018 
------------------------------------  ------------------------  ------------  ---  ------------- 
Balance of unallotted securities under scheme(s) from 
 previous return:                                                                     13,609,372 
--------------------------------------------------------------  -------------------------------- 
Plus: The amount by which the block scheme(s) has 
 been increased since the date of the last return (if 
 any increase has been applied for):                                                         Nil 
--------------------------------------------------------------  -------------------------------- 
Less: Number of securities issued/allotted under scheme(s) 
 during period (see LR3.5.7G):                                                         1,291,074 
--------------------------------------------------------------  -------------------------------- 
Equals: Balance under scheme(s) not yet issued/allotted 
 at end of period:                                                                    12,318,298 
--------------------------------------------------------------  -------------------------------- 
 
 
 
 
 
 
Name of applicant:                                              Shire plc 
--------------------------------------------------------------  ------------------------------------------------------------ 
                                                                Combined block listing in respect of the Shire Portfolio 
                                                                 Share Plan, the Shire Long Term Incentive Plan 2015 
Name of scheme:                                                  and the Shire Global Employee Stock Purchase Plan. 
--------------------------------------------------------------  ------------------------------------------------------------ 
Period of return:                     From:                     May 23, 2018          To:       November 22, 2018 
------------------------------------  ------------------------  --------------------  --------  ---------------------------- 
Balance of unallotted securities under scheme(s) from 
 previous return:                                                                                                  3,000,000 
--------------------------------------------------------------  ------------------------------------------------------------ 
Plus: The amount by which the block scheme(s) has 
 been increased since the date of the last return (if 
 any increase has been applied for):                                                                                     Nil 
--------------------------------------------------------------  ------------------------------------------------------------ 
                                                                                             Shire Portfolio Share Plan: Nil 
Less: Number of securities issued/allotted under scheme(s)                          Shire Long Term Incentive Plan 2015: Nil 
 during period (see LR3.5.7G):                                                Shire Global Employee Stock Purchase Plan: Nil 
--------------------------------------------------------------  ------------------------------------------------------------ 
Equals: Balance under scheme(s) not yet issued/allotted 
 at end of period:                                                                                                 3,000,000 
--------------------------------------------------------------  ------------------------------------------------------------ 
 
   Sarah Rixon 
 
   Senior Company Secretarial Assistant 
 
   For further information please contact: 
 
 
 
 
Investor Relations 
Christoph Brackmann   christoph.brackmann@shire.com   +41 41 288 41 29 
Sun Kim               sun.kim@shire.com                +1 617 588 8175 
Scott Burrows         scott.burrows@shire.com          +41 41 288 4195 
 
Media 
Katie Joyce           kjoyce@shire.com                 +1 781 482 2779 
 
 
 
   NOTES TO EDITORS 
 
   About Shire 
 
   Shire is the global biotechnology leader serving patients with rare 
diseases and specialized conditions. We seek to push boundaries through 
discovering and delivering new possibilities for patient communities who 
often have few or no other champions. Relentlessly on the edge of what's 
next, we are serial innovators with a diverse pipeline offering fresh 
thinking and new hope. Serving patients and partnering with healthcare 
communities in over 100 countries, we strive to be part of the entire 
patient journey to enable earlier diagnosis, raise standards of care, 
accelerate access to treatment, and support patients. Our diverse 
portfolio of therapeutic areas includes Immunology, Hematology, Genetic 
Diseases, Neuroscience, Internal Medicine, and Ophthalmics. 
 
 
 
   Championing patients is our call to action - it brings the opportunity - 
and responsibility - to change people's lives. 
 
   www.shire.com 
 
 
 
 

(END) Dow Jones Newswires

November 23, 2018 04:15 ET (09:15 GMT)

Copyright (c) 2018 Dow Jones & Company, Inc.
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