Stryker Corp. (SYK) signed a definitive agreement to acquire Orthovita Inc. (VITA), a maker of orthobiologic and biosurgery products, for about $304 million in cash.

Shareholders will receive $3.85 for each share, a 41% premium over Friday's close. The deal also includes $12 million in debt. Shares surged premarket, matching the offer price and last traded above it about a year ago. Stryker, meanwhile, was inactive and closed Friday at $63.28.

Orthovita competes in the $5 billion orthobiologics market, offering synthetic bone grafts through its Vitoss product and also competes in vertebral augmentation with its Cortoss product.

Stryker's big business for replacement hips and knees has posted flat sales recently as the orthopedics market struggles to overcome a slowdown caused by economic turmoil and high unemployment.

"With this acquisition we are meaningfully expanding our orthobiologics product portfolio and strengthening our competitive position in key segments of the Spine, Orthopaedics and Biosurgery markets," Chief Executive Stephen P. MacMillan said.

Stryker plans to launch an all-cash tender offer within 10 business days, which will be completed in the second quarter.

Orthovita has recommended shareholders accept the offer, and those who hold about 14.5% of the company's shares outstanding have already committed.

Stryker reported last month that its first-quarter earnings fell 4.4% on acquisition and integration-related charges, but the company posted a double-digit sales increase behind continued growth in its medical-supplies franchise and a newly acquired business.

-By Lauren Pollock, Dow Jones Newswires; 212-416-2356; lauren.pollock@dowjones.com

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