Zomedica Announces Completion of Initial Development of a Lymphoma Assay for its Canine Cancer Liquid Biopsy Platform
13 Junio 2019 - 5:55AM
Zomedica Pharmaceuticals Corp. (NYSE American: ZOM) (TSX-V: ZOM), a
veterinary diagnostic and pharmaceutical company, today announced
that it has completed initial development work on a blood-borne
lymphoma cancer assay intended for use with its canine cancer
liquid biopsy platform.
According to the American Veterinary Medical Association, one in
four dogs will develop cancer during their lifetime. Lymphomas
represent approximately 10-25% of all cancers diagnosed in
dogs.
The lymphoma assay, designated ZM-022, is designed to identify
specific genetic abnormalities using fluorescence in situ
hybridization (FISH). FISH tests are regularly used for cancers in
human medicine, such as the HER2 breast cancer test. The assay is
being developed for use on Zomedica’s liquid biopsy platform, which
is expected to be available for sale in 2020.
As previously announced, Zomedica is also developing assays for
the detection of hemangiosarcoma and osteosarcoma for use with its
liquid biopsy platform, designated ZM-017. Lymphoma, osteosarcoma,
and hemangiosarcoma are three of the top five most commonly
diagnosed malignant canine cancers.
Zomedica expects that the out-of-pocket cost incurred by pet
owners for these assays will be a fraction of the cost of current
testing methods, which can be thousands of dollars depending on the
presentation.
Lymphoma often presents with swollen lymph nodes, allowing for
fine needle aspiration of the tumor for initial diagnosis.
Zomedica’s biomarker study design included samples from B-cell and
T-cell tumors as well as peripheral blood samples from lymphoma
patients and healthy patients. Zomedica was able to identify these
genetic abnormalities consistently to differentiate between
cancerous and non-cancerous B-cells and T-cells on a peripheral
blood draw. Additional prognostic tests involve the removal of a
lymph node and can take at least a week or longer to obtain,
delaying treatment and allowing for progression of this aggressive
form of cancer.
Zomedica has submitted patent applications for its lymphoma
assay.
“We are excited to add this important assay to the development
work we are doing on our liquid biopsy platform,” said Dr.
Stephanie Morley, Chief Operations Officer and Vice President of
Product Development. “We expect that if we successfully complete
the development of these assays, our liquid biopsy platform will
offer veterinarians and their teams the opportunity to make better
treatment decisions more quickly and at a lower cost compared to
existing technologies, creating better outcomes for their patients
and pet owners. The development of multiple assays for our liquid
biopsy platform demonstrates the versatility of the platform.”
Zomedica anticipates beginning verification and branding efforts
for its lymphoma assay by the fourth quarter of 2019 with
validation to commence in 2020. Assuming successful completion of
validation, Zomedica expects to commence commercialization of this
platform and its initial assays in 2020.
About ZomedicaBased in Ann Arbor,
Michigan, Zomedica (NYSE American: ZOM) (TSX-V: ZOM) is a
veterinary diagnostic and pharmaceutical company creating products
for companion animals (canine, feline and equine) by focusing on
the unmet needs of clinical veterinarians. Zomedica’s product
portfolio will include novel diagnostics and innovative
therapeutics that emphasize patient health and practice health.
With a team that includes clinical veterinary professionals, it is
Zomedica’s mission to give veterinarians the opportunity to lower
costs, increase productivity, and grow revenue while better serving
the animals in their care. For more information, visit
www.ZOMEDICA.com.
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those expressed in the forward-looking information include, but are
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assays currently under development, including our lymphoma assay,
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results as reliable as those provided by existing reference
laboratory equipment, risks related to the verification, branding
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Investor Relations Contact: Shameze Rampertab,
CPA, CA srampertab@zomedica.com +1 647.283.3630PCG Advisory Group
Kirin Smith, COO ksmith@pcgadvisory.com +1 646.863.6519
Media Contact: Christy Penkacpenka@zomedica.com+1
734.369.2555
American Veterinary Medical Association. Cancer in Pets.Burns,
Meghan E. What’s new in canine lymphoma. DVM360, July 17, 2017.
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