Bonerge Initiates the Human Clinical Trail Plans for GlucoSober®-Dihydroberberine and BeFisetin®-Fisetin
31 Julio 2024 - 1:40PM
Business Wire
Bonerge is excited to announce the initiation of clinical trials
for its high-quality brand ingredients, including GlucoSober and
BeFisetin. These trials aim to substantiate the efficacy and safety
of the products, providing more reliable options for the
market.
In an era where health consciousness is on the rise, consumers
are increasingly seeking high-quality dietary supplements. Bonerge
is embarking on several clinical trials to make evidence-based
ingredients that meet the needs of consumers.
Key Products Undergoing Clinical Trials
BeFisetin®: This high-quality Fisetin with total
flavonoids greater than 99%, Fisetin content greater than 98% and
impurity smaller than 1%. Previous preclinical studies have shown
that fisetin can effectively clear senescent cells, targeting one
of the hallmarks of aging. [1,2] The upcoming clinical trials will
further investigate BeFisetin's potential benefits to support the
market.
GlucoSober®: An ultra-pure Dihydroberberine with stable
quality, GlucoSober is a derivative of the popular weight-loss
supplement Berberine. While Berberine has a bioavailability of less
than 1%, Dihydroberberine has shown more effective. [3] As an
ultrapure product, higher purity means more active ingredients that
are packed. GlucoSober is set to be the product to undergo human
clinical trials to validate the benefits of Dihydroberberine.
Additionally, Bonerge will conduct clinical research on product
formulations to investigate the synergistic effects of ingredients
to meet personalized demand. Further details will be announced.
The Initiates of Choosing Clinical Trials Exploring the
functions and applications of ingredients requires collaboration
among scientists, manufacturers, and brands. As the mainstream
Dihydroberberine supplier, Bonerge continues to explore
scientifically proven health longevity and metabolic health
ingredients. Bonerge partners with leading brands to ensure
consumers have access to high-quality products that help them to
maintain a balanced blood glucose level.
About Bonerge Bonerge is one innovative team and lab
specialized in longevity and metabolic health ingredients. Bonerge
closely follow up on the latest anti-aging science, develop novel
longevity ingredients. Bonerge is guided by 12 hallmarks of aging.
Live longer and healthier.
References 1. Yousefzadeh, Matthew J et al. “Fisetin is a
senotherapeutic that extends health and lifespan.” EBioMedicine
vol. 36 (2018): 18-28. doi:10.1016/j.ebiom.2018.09.015
2. López-Otín, Carlos et al. “Hallmarks of aging: An expanding
universe.” Cell vol. 186,2 (2023): 243-278.
doi:10.1016/j.cell.2022.11.001
3. Xu, Hong-Yu et al. “Nanoemulsion improves hypoglycemic
efficacy of berberine by overcoming its gastrointestinal
challenge.” Colloids and surfaces. B, Biointerfaces vol. 181
(2019): 927-934. doi:10.1016/j.colsurfb.2019.06.006
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Cecilia Yang +1 (949) 712-7328 sales@bonerge.com