TIDMAZM 
 
RNS Number : 5904N 
Alizyme PLC 
19 February 2009 
 

+----------------------------------------+----------------------------------------+ 
| For Immediate Release                  |                       19 February 2009 | 
+----------------------------------------+----------------------------------------+ 
 
 
ALIZYME PLC 
 
 
BLOCK LISTING SIX MONTHLY RETURN 
 
 
 
 
+-------------------+--------+-----------+--------+------------------+ 
| Name of                    | Alizyme plc                           | 
| applicant:                 |                                       | 
+----------------------------+---------------------------------------+ 
| Name of scheme:            | The Alizyme plc 2001                  | 
|                            | Unapproved Executive                  | 
|                            | Share Option Scheme                   | 
+----------------------------+---------------------------------------+ 
| Period            | From:  | 19 August | To:    | 18 February 2009 | 
| of                |        | 2008      |        |                  | 
| return:           |        |           |        |                  | 
+-------------------+--------+-----------+--------+------------------+ 
| Balance under              | 68,183                                | 
| scheme from                |                                       | 
| previous                   |                                       | 
| return:                    |                                       | 
+----------------------------+---------------------------------------+ 
| The amount by              | Nil                                   | 
| which the block            |                                       | 
| scheme has been            |                                       | 
| increased, if              |                                       | 
| the scheme has             |                                       | 
| been increased             |                                       | 
| since the date             |                                       | 
| of the last                |                                       | 
| return:                    |                                       | 
+----------------------------+---------------------------------------+ 
| Number of                  | Nil                                   | 
| securities issued/allotted |                                       | 
| under scheme during        |                                       | 
| period:                    |                                       | 
+----------------------------+---------------------------------------+ 
| Balance under              | 68,183                                | 
| scheme not yet             |                                       | 
| issued/allotted            |                                       | 
| at end of                  |                                       | 
| period:                    |                                       | 
+----------------------------+---------------------------------------+ 
| Number and                 | 800,000 ordinary shares               | 
| class of                   | of 2p each, admitted on               | 
| securities                 | 12 February 2007                      | 
| originally                 |                                       | 
| listed and the             |                                       | 
| date of                    |                                       | 
| admission:                 |                                       | 
+----------------------------+---------------------------------------+ 
| Total number of            | 221,098,686 ordinary                  | 
| securities in              | shares of 2p each fully               | 
| issue at the               | paid                                  | 
| end of the                 |                                       | 
| period:                    |                                       | 
+-------------------+--------+-----------+--------+------------------+ 
 
 
+-----------+-----------------+ 
| Name      | Nick            | 
| of        | Blech,          | 
| contact:  | Company         | 
|           | Secretary       | 
+-----------+-----------------+ 
| Address   | Alizyme         | 
| of        | plc,            | 
| contact:  | Granta Park,    | 
|           | Great           | 
|           | Abington,       | 
|           | Cambridge, CB21 | 
|           | 6GX             | 
+-----------+-----------------+ 
| Telephone | 01223 896000    | 
| number of |                 | 
| contact:  |                 | 
+-----------+-----------------+ 
 
 
 
 
 
This information is provided by RNS 
            The company news service from the London Stock Exchange 
   END 
 
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