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| Fecha | Nombre del titular | Acciones transaccionadas | Rango de valor ($) | Tipo de transacción | Rango de precio ($) | Acciones al cierre del informe | % de cambio |
|---|---|---|---|---|---|---|---|
| 2026-06-12 | Dr. Ming YanCTO & Director | -135.89k | 0.00 | Other Disposition | - | 4.80M | -2.75% |
| 2026-06-10 | Mr. Jack T. BallTitular individual | 43.97k | 0.00 | Derivative Exercise and Retained Stock | - | 86.68k | 102.97% |
| 2026-06-10 | Dr. Vera ImperIndependent Director | 43.97k | 0.00 | Derivative Exercise and Retained Stock | - | 59.68k | 279.98% |
| 2026-06-10 | Ms. Deborah J. NeffLead Independent Director | 43.97k | 0.00 | Derivative Exercise and Retained Stock | - | 59.68k | 279.98% |
| 2026-06-10 | Mr. Michael Bria HolderIndependent Director | 43.97k | 0.00 | Derivative Exercise and Retained Stock | - | 60.69k | 262.98% |
| 2026-05-18 | Mr. Michael Bria HolderIndependent Director | 1.45k | 0.00 | Derivative Exercise and Retained Stock | - | 16.72k | 9.52% |
| 2026-05-18 | Dr. Richard ChinIndependent Director | 6.11k | 0.00 | Derivative Exercise and Retained Stock | - | 22.39k | 37.50% |
| 2026-05-18 | Dr. Ming YanCTO & Director | 16.65k | 0.00 | Derivative Exercise and Retained Stock | - | 4.93M | 0.34% |
| 2026-05-18 | Dr. Ming YanCTO & Director | -5.53k | 19.64k | Derivative Exercise and Sale | 3.55 | 4.93M | - |
| 2026-05-18 | Dr. Philippe BusqueTitular individual | 7.78k | 0.00 | Derivative Exercise and Retained Stock | - | 43.47k | 21.80% |
| 2026-05-18 | Dr. Philippe BusqueTitular individual | -2.69k | 9.53k | Derivative Exercise and Sale | 3.55 | 43.47k | - |
| 2026-05-18 | Dr. Wenbin JiangPresident, CEO & Chairman of the Board | 54.52k | 0.00 | Derivative Exercise and Retained Stock | - | 5.48M | 1.01% |
| 2026-05-18 | Dr. Wenbin JiangPresident, CEO & Chairman of the Board | -25.54k | 90.67k | Derivative Exercise and Sale | 3.55 | 5.48M | - |
| 2026-05-18 | Mr. William D. McCombeCFO | 16.49k | 0.00 | Derivative Exercise and Retained Stock | - | 111.18k | 17.42% |
| 2026-05-18 | Mr. William D. McCombeCFO | -9.23k | 32.76k | Derivative Exercise and Sale | 3.55 | 111.18k | - |
| 2026-05-18 | Ms. Valerie T. BarnettChief Legal Officer & Corporate Secretary | 15.58k | 0.00 | Derivative Exercise and Retained Stock | - | 150.01k | 11.59% |
| 2026-05-18 | Ms. Valerie T. BarnettChief Legal Officer & Corporate Secretary | -8.72k | 30.95k | Derivative Exercise and Sale | 3.55 | 150.01k | - |
| 2026-03-13 | Dr. Ming YanCTO & Director | -1.18M | 0.00 | Other Disposition | - | 4.92M | -19.30% |
| 2026-03-10 | Dr. Richard ChinIndependent Director | 6.11k | 0.00 | Derivative Exercise and Retained Stock | - | 16.29k | 60.00% |
| 2026-03-10 | Ms. Valerie T. BarnettChief Legal Officer & Corporate Secretary | 17.97k | 0.00 | Derivative Exercise and Retained Stock | - | 134.44k | 15.43% |
| 2026-03-10 | Ms. Valerie T. BarnettChief Legal Officer & Corporate Secretary | -11.75k | 49.69k | Derivative Exercise and Sale | 4.23 | 134.44k | - |
| 2026-03-10 | Dr. Philippe BusqueTitular individual | 6.79k | 0.00 | Derivative Exercise and Retained Stock | - | 35.69k | 23.48% |
| 2026-03-10 | Dr. Philippe BusqueTitular individual | -3.04k | 12.87k | Derivative Exercise and Sale | 4.23 | 35.69k | - |
| 2026-03-10 | Dr. Wenbin JiangPresident, CEO & Chairman of the Board | 62.86k | 0.00 | Derivative Exercise and Retained Stock | - | 5.42M | 1.17% |
| 2026-03-10 | Dr. Wenbin JiangPresident, CEO & Chairman of the Board | -20.99k | 88.78k | Derivative Exercise and Sale | 4.23 | 5.42M | - |
| 2026-03-10 | Mr. William D. McCombeCFO | 13.97k | 0.00 | Derivative Exercise and Retained Stock | - | 94.69k | 17.31% |
| 2026-03-10 | Mr. William D. McCombeCFO | -9.75k | 41.23k | Derivative Exercise and Sale | 4.23 | 94.69k | - |
| 2026-03-10 | Dr. Ming YanCTO & Director | 17.67k | 0.00 | Derivative Exercise and Retained Stock | - | 6.09M | 0.29% |
| 2026-03-10 | Dr. Ming YanCTO & Director | -7.73k | 32.70k | Derivative Exercise and Sale | 4.23 | 6.09M | - |
| 2026-03-10 | Mr. Michael Bria HolderIndependent Director | 2.91k | 0.00 | Derivative Exercise and Retained Stock | - | 15.27k | 23.53% |
| 2026-02-18 | Dr. Wenbin JiangPresident, CEO & Chairman of the Board | 3.18k | 0.00 | Derivative Exercise and Retained Stock | - | 5.36M | 0.06% |
| 2026-02-18 | Dr. Wenbin JiangPresident, CEO & Chairman of the Board | -1.34k | 5.62k | Derivative Exercise and Sale | 4.20 | 5.36M | - |
| 2026-02-18 | Dr. Ming YanCTO & Director | 937.00 | 0.00 | Derivative Exercise and Retained Stock | - | 6.07M | 0.02% |
| 2026-02-18 | Dr. Ming YanCTO & Director | -395.00 | 1.66k | Derivative Exercise and Sale | 4.20 | 6.07M | - |
| 2026-02-18 | Ms. Valerie T. BarnettChief Legal Officer & Corporate Secretary | 821.00 | 0.00 | Derivative Exercise and Retained Stock | - | 116.46k | 0.71% |
| 2026-02-18 | Ms. Valerie T. BarnettChief Legal Officer & Corporate Secretary | -525.00 | 2.21k | Derivative Exercise and Sale | 4.20 | 116.46k | - |
| 2025-11-18 | Dr. Ming YanCTO & Director | 15.91k | 0.00 | Derivative Exercise and Retained Stock | - | 6.07M | 0.26% |
| 2025-11-18 | Dr. Ming YanCTO & Director | -5.12k | 28.33k | Derivative Exercise and Sale | 5.53 | 6.07M | - |
| 2025-11-18 | Dr. Philippe BusqueTitular individual | 5.49k | 0.00 | Derivative Exercise and Retained Stock | - | 28.90k | 23.43% |
| 2025-11-18 | Dr. Philippe BusqueTitular individual | -1.89k | 10.42k | Derivative Exercise and Sale | 5.53 | 28.90k | - |
| 2025-11-18 | Ms. Valerie T. BarnettChief Legal Officer & Corporate Secretary | 16.49k | 0.00 | Derivative Exercise and Retained Stock | - | 115.64k | 16.63% |
| 2025-11-18 | Ms. Valerie T. BarnettChief Legal Officer & Corporate Secretary | -7.82k | 43.23k | Derivative Exercise and Sale | 5.53 | 115.64k | - |
| 2025-11-18 | Mr. William D. McCombeCFO | 13.14k | 0.00 | Derivative Exercise and Retained Stock | - | 80.71k | 19.45% |
| 2025-11-18 | Mr. William D. McCombeCFO | -6.23k | 34.44k | Derivative Exercise and Sale | 5.53 | 80.71k | - |
| 2025-11-18 | Dr. Wenbin JiangPresident, CEO & Chairman of the Board | 42.24k | 0.00 | Derivative Exercise and Retained Stock | - | 5.36M | 0.79% |
| 2025-11-18 | Dr. Wenbin JiangPresident, CEO & Chairman of the Board | -27.41k | 151.56k | Derivative Exercise and Sale | 5.53 | 5.36M | - |
| 2025-11-18 | Mr. Michael Bria HolderIndependent Director | 2.18k | 0.00 | Derivative Exercise and Retained Stock | - | 12.36k | 21.43% |
| 2025-11-18 | Dr. Richard ChinIndependent Director | 6.11k | 0.00 | Derivative Exercise and Retained Stock | - | 10.18k | 150.01% |
| 2025-08-18 | Dr. Ming YanCTO & Director | 15.29k | 0.00 | Derivative Exercise and Retained Stock | - | 6.06M | 0.25% |
| 2025-08-18 | Dr. Ming YanCTO & Director | -5.74k | 23.30k | Derivative Exercise and Sale | 4.06 | 6.06M | - |
| 2025-08-18 | Dr. Philippe BusqueTitular individual | 4.50k | 0.00 | Derivative Exercise and Retained Stock | - | 23.42k | 23.78% |
| 2025-08-18 | Dr. Philippe BusqueTitular individual | -2.87k | 11.66k | Derivative Exercise and Sale | 4.06 | 23.42k | - |
| 2025-08-18 | Ms. Valerie T. BarnettChief Legal Officer & Corporate Secretary | 15.48k | 0.00 | Derivative Exercise and Retained Stock | - | 99.15k | 18.50% |
| 2025-08-18 | Ms. Valerie T. BarnettChief Legal Officer & Corporate Secretary | -8.83k | 35.85k | Derivative Exercise and Sale | 4.06 | 99.15k | - |
| 2025-08-18 | Dr. Wenbin JiangPresident, CEO & Chairman of the Board | 52.68k | 0.00 | Derivative Exercise and Retained Stock | - | 5.31M | 1.00% |
| 2025-08-18 | Dr. Wenbin JiangPresident, CEO & Chairman of the Board | -16.96k | 68.85k | Derivative Exercise and Sale | 4.06 | 5.31M | - |
| 2025-08-18 | Mr. William D. McCombeCFO | 11.83k | 0.00 | Derivative Exercise and Retained Stock | - | 67.57k | 21.21% |
| 2025-08-18 | Mr. William D. McCombeCFO | -7.55k | 30.64k | Derivative Exercise and Sale | 4.06 | 67.57k | - |
| 2025-08-18 | Mr. Michael Bria HolderIndependent Director | 2.18k | 0.00 | Derivative Exercise and Retained Stock | - | 10.18k | 27.27% |
| 2025-08-18 | Dr. Richard ChinIndependent Director | 4.07k | 0.00 | Derivative Exercise and Retained Stock | - | 4.07k | - |
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