16 October 2020

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("IXICO" or the "Company")

IXICO and NYU Langone Health sign agreement to develop

novel imaging markers in multiple system atrophy

IXICO plc (AIM: IXI), the data analytics company delivering insights in neuroscience, announces that it has entered into an agreement with NYU Langone Health to support a trial to determine if the immunosuppressant drug Sirolimus - approved by the FDA to prevent organ transplant rejection and for the treatment of a rare and progressive lung disease called lymphangioleiomiomatosis - is also able to slow the progression of disease in people with Multiple System Atrophy (MSA). Working with NYU Langone clinicians and researchers, the trial will help develop biomarkers for MSA from magnetic resonance imaging (MRI).

MSA is a condition of the central nervous system that causes gradual damage to nerve cells in the brain. The project involves application of IXICO's existing MSA analysis solutions on retrospectively collected MRI data from patients with MSA, dementia with Lewy Bodies, Parkinson's disease, and Progressive Supranuclear Palsy as well as the joint development of a novel solution to analyse susceptibility weighted imaging (SWI).

Dr Robin Wolz, Senior Vice President for Science and Innovation at IXICO plc, commented: "This collaboration will help to accelerate the quest for new treatments for Multiple System Atrophy by bringing together some of the leading researchers in the field from both academia and industry with the specific goal of developing new tools to better understand and characterise this debilitating disease."

Dr. Horacio Kaufman, the Felicia B. Axelrod Professor of Dysautonomia Research at NYU Grossman School of Medicine and Director of the Dystonomia Center at NYU Langone Health, added: "IXICO will bring its expertise in neuroimaging and AI to support the development and validation of new biomarkers which in turn will help to identify the most promising treatments and bring these to patients sooner."

For further information please contact:

 IXICO plc                                                +44 (0)20 3763 7498 
 Giulio Cerroni, Chief Executive Officer 
  Grant Nash, Chief Financial Officer 
 Cenkos Securities PLC (Nominated adviser 
  and sole broker)                                        +44 (0)20 7397 8900 
 Giles Balleny / Max Gould (Corporate 
 Michael F Johnson / Russell Kerr 
 Walbrook PR Ltd                                          +44 (0)20 7933 8780 
 Paul McManus / Lianne Cawthorne                         IXICO@walbrookpr.com 
 Alice Woodings 


IXICO is dedicated to delivering insights in neuroscience. Our purpose is to advance medicine and human health by turning data into clinically meaningful information, providing valuable new insights in neuroscience and our goal is to be a leading proponent of artificial intelligence in medical image analysis. We will achieve this by developing and deploying breakthrough data analytics, at scale, through our remote access technology platform, to improve the return on investment in drug development and reduce risk and uncertainty in clinical trials for our pharmaceutical clients.

   More information is available on   www.IXICO.com and follow us on Twitter @IxicOplc 

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(END) Dow Jones Newswires

October 16, 2020 02:00 ET (06:00 GMT)