CHAPMAN AND CUTLER LLP 111 WEST MONROE STREET
CHICAGO, ILLINOIS 60603

August 30, 2012

Securities and Exchange Commission
100 F Street, N.E.
Washington, DC 20549

Re: First Trust Exchange-Traded Fund VI
(Registration Nos. 333-182308, 811-22717)

Ladies and Gentlemen:

On behalf of First Trust Exchange-Traded Fund VI (the "Registrant"), we are transmitting for electronic filing pursuant to Rule 497(e) under the Securities Act of 1933, as amended, the exhibits containing interactive data format risk/return summary information that mirrors the risk/return summary information in the form of Prospectus for the Registrant filed pursuant to Rule 497(c) on August 14, 2012. The Registration Statement relates to Multi-Asset Diversified Income Index Fund, a series of the Registrant.

If you have any questions or comments, please telephone the undersigned at
(312) 845-3484.

Very truly yours,

CHAPMAN AND CUTLER LLP

By: /s/ Morrison C. Warren
 ----------------------------------
 Morrison C. Warren

Enclosures

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