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Sagiment Biosciences Inc

Sagiment Biosciences Inc (SGMT)

4.73
-0.45
(-8.69%)
Cerrado 17 Noviembre 3:00PM
4.70
-0.03
(-0.63%)
Fuera de horario: 6:38PM

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SGMT Discussion

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TechandBio TechandBio 2 semanas hace
I would be shocked if the CFO did an offering at these levels.

I think partnership or buyout with Madrigal is in the works.

Core Holding!

$SGMT
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PonkenPlonken PonkenPlonken 1 mes hace
Looking good here. Keep in mind offering was done at 12.50 strike in January via Goldman. Great NASH science... liver fat synthesis oral administrationi
https://www.globenewswire.com/news-release/2024/01/26/2817557/0/en/Sagimet-Biosciences-Announces-Pricing-of-Public-Offering-of-Series-A-Common-Stock.html
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tw0122 tw0122 1 mes hace
21 m float $5.12 + 14%
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TechandBio TechandBio 1 mes hace
We are just getting started I pounded the table to load up in the mid 2's low 3's
LFG!
$SGMT
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TechandBio TechandBio 1 mes hace
Fortunes to be made with the ones who have balls of fortitude buy the fear and make the big money !

$SGMT
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TechandBio TechandBio 1 mes hace
LFG. Happy Friday!

$SGMT
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TechandBio TechandBio 1 mes hace
Loaded to the Gills!

Will wait for the buyout at 1-2 Billion by 2027

$SGMT
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TechandBio TechandBio 1 mes hace
want one more chunk of shares under $4.00 this week!

$SGMT
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TechandBio TechandBio 1 mes hace
Reached 300K shares Long! Blessed

$SGMT
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TechandBio TechandBio 1 mes hace
Another 20k at $4.00 added already this morning thank you! bless!

$SGMT
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TechandBio TechandBio 1 mes hace
adding more today!

$SMGT
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TechandBio TechandBio 1 mes hace
Added 18k end of the day under $4.00 up to 257k shares Largest Holding after today!

$SGMT
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TechandBio TechandBio 1 mes hace
Thierry Chauche - New CFO SGMT 2024

Thierry Chauche :
Vice President, Head of Strategic FP&A at Alexion Pharmaceuticals, Inc.


$39 billion
In the largest pharmaceutical deal of the year, British pharmaceutical giant AstraZeneca has acquired American biotech firm and rare diseases specialist Alexion for $39 billion.

The total consideration paid to the Alexion shareholders was approximately $13.3bn in cash and 236,321,411 new AstraZeneca shares (approximately 94% of which will be represented by new AstraZeneca American Depositary Shares (ADSs)).

Provention Bio Announces Appointment of Thierry Chauche as Chief Financial Officer:
Provention Bio in its $2.9 billion acquisition by Sanofi, among other achievements.

Whats even more interesting is that SGMT believes that as the trials continue they will show better efficacy than AKRO which is a IV infusion with a market cap of 2 Billion SGMT drug is three times more effective than MDGL drug hence the https://ir.sagimet.com/news-releases/news-release-details/sagimet-receives-fda-breakthrough-therapy-designation

Another catalyst is Phase 2 MASH in Pediatric look to start Phase 2 in 2025
SGMT drugDenifanstat Combo Data with GLP1 and THR Betas knock it out of the park.
https://sagimet.com/posterspublications/

It Looks like the new CFO came in to negotiate a buyout there are big hitters on the board of Directors including Tim Walbert:
Mr. Walbert has nearly 30 years of biotechnology and industry experience. He joins Sagimet’s board following a 15-year tenure as president, chief executive officer, and chairman of the board at Horizon Therapeutics, which he built from inception to a leading rare disease company. In 2023, Amgen acquired Horizon for $28 billion, and Mr. Walbert currently serves as a senior advisor to Amgen.


Paul Hoelscher

Mr. Hoelscher served as executive vice president and chief financial officer of Horizon Therapeutics from 2014 to 2022, prior to the company’s acquisition by Amgen. Prior to joining Horizon, Mr. Hoelscher held multiple financial executive roles in various consumer products, retail and business services companies, as well as working in the audit practice of KPMG LLP.

The previous CMO of GIlead who just retired from Gilead a few months ago is also on the board:

Merdad Parsey, MD, PhD

Dr. Parsey joined Sagimet Biosciences as president, chief executive officer and board director in September 2010 and stepped down from the role of president and chief executive officer in 2015. He is currently Chief Medical Officer at Gilead Sciences, Inc. Previously, Dr. Parsey held positions at Genentech, Inc., a member of the Roche Group, Sepracor, Regeneron and Merck, Inc. He has worked on multiple development and post-marketing programs from initial human trials to NDA/BLA submissions in respiratory, inflammation, virology, neurology, ophthalmology and gastrointestinal diseases.

Looks like MDGL GILD AMGN NVO LLY could be potential suitors the magnitude of this oral molecule is a next level blockbuster for a variety of big indications>

https://sagimet.com/about/board-of-directors/

https://sagimet.com/about/executives/

AKRO 2 Billion market cap
ETNB 720 Million market cap
SGMT 130 Million market cap with a versatile fat syntheizer molecule that can treat a variety of diseases including a wide array of oncology indications.

Nearly 60 Million shares traded last week A buyout is in the works that why thierry chauche was brought on as the CFO for SGMT this year.


An example of AKRO history:
$SGMT We reached step #3

Akero:
#1 - Sep 13, 2022 Efruxifermin phase 2b results
#2 - Sep 14, 2022 - offering
#3 - Dec 8 2022 - Efruxifermin Granted FDA Breakthrough Therapy Designation
#4 - Mar 29, 2023 - Announces Positive End-of-Phase 2 Meeting with the FDA and SYNCHRONY Phase 3 Program
#5 - May 16, 2023 - one more offering
#6 - Dec 18, 2023 - Phase 3 - first patient dosed.

Second example is ETNB 89 Bio:
$SGMT Similar sequence of steps, but for 89Bio


#1 - Mar 22 2023 - pegozafermin phase 2b results
#2 - Mar 22 2023 - offering
#3 - Sep 21 2023 - FDA has Granted Breakthrough Therapy Designation to pegozafermin
#4 - Dec 04 2023 - Alignment with the FDA and EMA on Phase 3 Program for Pegozafermin in Nonalcoholic Steatohepatitis (NASH)
#5 - Dec 12 2023 - one more offering
#6 - Mar 12 2024 - phase 3 first patient dozed

In this case either a buyout a partnership should happen sooner than later with catalyst of completion of FDA meeting on Phase 3 design complete and start of Phase 3

Price Target

The average one-year price target for Sagimet Biosciences Inc. is $33.25. The forecasts range from a low of $6.06 to a high of $70.35
When Goldman Lowered their PT on SGMT is when I started accumulating shares!

$SGMT
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Pip611 Pip611 1 mes hace
This is just the beginning. $10+ before the end of the year.
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tw0122 tw0122 2 meses hace
Pump it 3.60s
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ollik78 ollik78 2 meses hace
Presentation Tomorrow
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Pip611 Pip611 2 meses hace
Big move today, but I don’t see any news. Anyone know what’s going on?
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Monksdream Monksdream 2 meses hace
SGMT under $4
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Pip611 Pip611 5 meses hace
Anyone know why this has been tanking so bad the last couple weeks?
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Monksdream Monksdream 7 meses hace
SGMT under $5
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AGORDON AGORDON 8 meses hace
Sagimet Biosciences (Nasdaq: SGMT $6.25)
Buy recommendation.

Market cap = $199M
Cash = $210M+ (Just raised $112M through a secondary offering)
Estimated cash burn = ($25)/year
Lead product = Denifanstat an oral, once daily pill and selective first-in-class FASN inhibitor in development for the treatment of nonalcoholic steatohepatitis (NASH).
Jan. 22, 2024 announced positive topline results from Phase 2b clinical trial of Denifanstat in Biopsy-confirmed F2/FS NASH.
The results are comparable to Madrigal's Resmitiron.
Ascletis collaboration agreement = Potential $122M in milestone payments as well as tiered royalties ranging from percentages in the high single digits to mid-teens on future net sales of Denifanstat, which is referred to as ASC40 in Greater China
Most AEs (adverse events) were Grade 1 or 2 (mild to moderate). There were no Grade 3 AEs.
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eneels01 eneels01 10 meses hace
See if $10 level holds. MC could drift upward later this year towards $1B area as company is similar to ETNB…
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dinogreeves dinogreeves 10 meses hace
Yup, got out at 16.25, thought they had enough in the coffers to push through this year. It was a good score while it lasted.
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TheFinalCD TheFinalCD 10 meses hace
Sagimet Biosciences Announces Pricing of Public Offering of Series A Common Stock
https://newsfilter.io/articles/sagimet-biosciences-announces-pricing-of-public-offering-of-series-a-common-stock-c3511595df124183e48b41923f34e655

Sagimet Biosciences Announces Proposed Public Offering of Series A Common Stock
https://ir.sagimet.com/news-releases/news-release-details/sagimet-biosciences-announces-proposed-public-offering-series
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gail gail 10 meses hace
congrats!
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dinogreeves dinogreeves 10 meses hace
Only down 5% for after hours. Nothing to sweat over.
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dinogreeves dinogreeves 10 meses hace
Three nice winners in my circle.
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dinogreeves dinogreeves 10 meses hace
Looks like another run tomorrow.
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gail gail 10 meses hace
that was fun! i love “bar charts as…



” i get a lot of good leads from that free website.
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gail gail 10 meses hace
hey dino, looks like we got a runner here, weeeee!!
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gail gail 10 meses hace
grabbed a few on the dip. hi all.
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dinogreeves dinogreeves 10 meses hace
Looks like easy 500% gainer today.
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dinogreeves dinogreeves 10 meses hace
What a great move and Baker Brothers in it, I simply got lucky at 11.38 with 2500 shares. Looks like billion dollar market cap is going to fetched here real soon.
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Awl416 Awl416 10 meses hace
That 20k block they filled at 9.69 before ripping

Yummy
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Awl416 Awl416 10 meses hace
Sagimet Biosciences Announces Positive Topline Results from Phase 2b FASCINATE-2 Clinical Trial of Denifanstat in Biopsy-Confirmed F2/F3 NASH
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