Agilent Technologies Introduces miRNA Microarrays Featuring Latest miRBase 21 Content
21 Octubre 2014 - 10:00AM
Business Wire
SurePrint miRNA Microarrays Provide
Comprehensive Coverage, Superior Data Reproducibility, Updated User
Content
Agilent Technologies Inc. (NYSE:A) today announced updates to
its SurePrint miRNA Microarrays to include targets from the latest
public miRNA miRBase database. The database, miRBase 21, contains
28,645 entries, including more than 15 percent in content added
from miRBase 20.
Agilent SurePrint miRNA Microarrays feature innovative labeling
and hairpin probe designs to provide exceptional sequence and size
discrimination.
MicroRNA, or miRNA, research has grown dramatically in the
effort to better understand gene regulation in diseases, such as
cancer. The availability of Agilent SurePrint human, mouse and rat
miRNA microarrays, with miRBase 21 targets, provides pre-designed
microarrays for the most commonly studied models. Any species in
the miRBase database can also be used to create a custom microarray
through the Web-based design tool eArray to include probe content
from the latest miRBase 21.
In a recently published miRQC study1, Agilent SurePrint miRNA
Microarrays were compared with various qPCR, next-generation
sequencing, and microarray platforms to benchmark performance.
Starting with only 100 ng of total RNA, Agilent miRNA microarrays
exhibited excellent performance with the highest titration
response, reproducibility and precision in accuracy while requiring
the lowest sample amount among the next-closest performing
assays.
“Providing the latest content, easy customizability and superior
performance in our miRNA microarrays reinforces the merits of our
SurePrint technology,” said Alessandro Borsatti, senior director of
Marketing for Agilent’s Diagnostics and Genomics group. “We
maintain our commitment to microarrays because they provide
well-proven and established workflows for scientists seeking the
greatest efficiency and cost-effectiveness for investigating
miRNAs.”
SurePrint miRNA Microarrays are part of the SurePrint product
family, including gene expression and comparative genomic
hybridization (CGH) microarrays. The breadth of microarray
applications is enhanced by the depth of Agilent’s genomic
workflow—from the 2100 Bioanalyzer and 2200 TapeStation for QC, to
SureScan Scanner for data acquisition, GeneSpring for data analysis
and AriaMX system for Real-Time PCR—to provide researchers a
complete solution.
To learn more about SurePrint miRNA Microarrays, visit:
www.agilent.com/genomics/miRNA21.
About Agilent in Genomics
Agilent is a global leader in target enrichment for
next-generation sequencing and genomic microarrays. The Agilent
SureSelect and HaloPlex target-enrichment systems enable
researchers to easily choose which segments of a genome to
sequence, avoiding the time and expense needed to sequence the
entire genome. HaloPlex offers a same-day sample-to-sequencer
workflow; SureSelect can accurately capture whole exomes and whole
methylomes in a single reaction. These are just two products
arising from Agilent’s expertise in synthesizing custom complex
mixtures of long oligonucleotides gained in microarray
manufacturing. Additional product lines built on this core
technology include microarrays for genome-wide measurement of gene
expression and for comparative genomics hybridization, as well as
SureFISH, a highly specific and sensitive product line for
oligonucleotide fluorescent in situ hybridization. In addition to
oligonucleotide-based products, Agilent offers a microfluidic
bioanalyzer to measure sample quality, and a full set of reagents,
hardware, methods and bioinformatics software for genomic
experiments.
For more information on Agilent’s complete line of Genomics
solutions, visit:
www.chem.agilent.com/en-US/Solutions/Genomics/Pages/default.aspx.
About Agilent Technologies
Agilent Technologies Inc. (NYSE:A) is a leader in chemical
analysis, life sciences, diagnostics, electronics and
communications. The company’s 20,600 employees serve customers in
more than 100 countries. Agilent had revenues of $6.8 billion in
fiscal 2013. Information about Agilent is available at
www.agilent.com.
On Sept. 19, 2013, Agilent announced plans to separate into two
publicly traded companies through a tax-free spinoff of its
electronic measurement business. The new company is named Keysight
Technologies, Inc. The separation is expected to be completed in
early November 2014.
Forward-Looking Statements
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in the Securities Exchange Act of 1934 and is subject to the safe
harbors created therein. The forward-looking statements contained
herein include, but are not limited to, information regarding the
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any forward-looking statement.
1 P. Mestdagh et al., Nature
Methods 11, 809–815 (2014)
NOTE TO EDITORS: Further technology, corporate citizenship and
executive news is available at www.agilent.com/go/news.
for Agilent Technologies Inc.Susan Berg, +1
408-553-7093susan_berg1@agilent.com
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