Exhibit 5.2
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Troutman Pepper Hamilton Sanders LLP
Suite 400, 301 Carnegie Center Princeton, NJ 08540-6227
troutman.com
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May 20, 2024
Johnson & Johnson
One Johnson & Johnson Plaza
New Brunswick, NJ 08933
Ladies and Gentlemen:
We have acted as special New Jersey counsel to Johnson & Johnson, a New Jersey corporation (the Company), in
connection with the issuance and sale by the Company of (i) $1,150,000,000 aggregate principal amount of 4.800% Notes due 2029, $1,150,000,000 aggregate principal amount of 4.900% Notes due 2031, $850,000,000 aggregate principal amount of 4.950%
Notes due 2034 and $850,000,000 aggregate principal amount of 5.250% Notes due 2054 (collectively, the USD Securities) to be offered pursuant to the Underwriting Agreement dated May 13, 2024, between J.P. Morgan Securities
LLC, BofA Securities, Inc., Citigroup Global Markets Inc. and the Company (the USD Underwriting Agreement), as supplemented by the Johnson & Johnson Underwriting Agreement Standard Provisions (Debt), dated May 13,
2024 (the Standard Provisions), which are incorporated by reference and deemed a part of the Underwriting Agreement, and (ii) 700,000,000 aggregate principal amount of 3.200% Notes due 2032, 800,000,000 aggregate
principal amount of 3.350% Notes due 2036 and 1,000,000,000 aggregate principal amount of 3.550% Notes due 2044 (collectively, the Euro Securities and together with the USD Securities, the Securities) to
be offered pursuant to the Underwriting Agreement dated May 14, 2024, between J.P. Morgan Securities plc, Citigroup Global Markets Limited, Deutsche Bank AG, London Branch and the Company (the Euro Underwriting Agreement and
together with the USD Underwriting Agreement, the Underwriting Agreements), as supplemented by the Standard Provisions, which are incorporated by reference and deemed a part of the Euro Underwriting Agreement. The Securities are
being issued pursuant to the Indenture, dated as of September 15, 1987 (the Base Indenture), by and between the Company and The Bank of New York Mellon Trust Company, N.A. (as successor to BNY Midwest Trust Company, which
succeeded Harris Trust and Savings Bank), as trustee (the Trustee), as supplemented by the First Supplemental Indenture, dated as of September 1, 1990, by and between the Company and the Trustee (the First
Supplemental Indenture), and the Second Supplemental Indenture, dated as of November 9, 2017, by and between the Company and the Trustee (the Second Supplemental Indenture and, together with the Base Indenture and
the First Supplemental Indenture, the Indenture).
In our capacity as special counsel, we have examined originals, or
copies certified or otherwise identified to our satisfaction, of the following, each dated of even date herewith unless otherwise noted (each, individually a Document and collectively the Documents):
(i) the Underwriting Agreements;