May 16, 2013


VIA EDGAR

Securities and Exchange Commission
Investment Company Division
100 F. Street, N.E.
Washington, DC 20549


Attention:   Office of Filings, Information & Consumer Services

Re: Henderson Global Funds (the “Trust”)
        (File Nos. 333-62270 and 811-10399)

To the Commission:

The Supplement is being filed to submit exhibits containing interactive data format risk/return summary information that mirrors the risk/return summary information in the filing pursuant to Rule 497(c) of the Prospectus dated April 30, 2013, for Henderson High Yield Opportunities Fund, as filed electronically via EDGAR with the Securities and Exchange Commission on May 2, 2013 (Accession # 0000891804-13-000619).

If you have any questions concerning this filing, you may contact me at (617) 662-3969.
 
Very truly yours,
 
/s/ Francine S. Hayes

Francine S. Hayes
Vice President and Managing Counsel
 
cc:           C. Yarbrough
 
 
 
 
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