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NanoViricides Inc

NanoViricides Inc (NNVC)

1.61
-0.07
(-4.17%)
Cerrado 14 Septiembre 3:00PM
1.61
0.00
(0.00%)
Fuera de horario: 6:53PM

Mejore su cartera: debates en tiempo real e ideas comerciales prácticas.

Estadísticas y detalles clave

Último Precio
1.61
Postura de Compra
-
Postura de Venta
-
Volume Operado de la Acción
126,312
1.59 Rango del Día 1.72
1.00 Rango de 52 semanas 7.86
Capitalización de Mercado [m]
Precio Anterior
1.68
Precio de Apertura
1.69
Última hora de negociación
Volumen financiero
US$ 211,793
Precio Promedio Ponderado
1.6767
Volumen promedio (3 m)
239,062
Acciones en circulación
11,814,000
Rendimiento del Dividendo
-
Ratio Precio/Utilidad
-2.21
Beneficio por acción (BPA)
-0.73
turnover
-
Beneficio neto
-8.59M

Acerca de NanoViricides Inc

Nanoviricides Inc is a nano-biopharmaceutical company which is engaged in discovering, developing, and commercializing therapeutics to advance the care of patients suffering from life-threatening viral infections. The company engaged in the application of nanomedicine technologies to the complex iss... Nanoviricides Inc is a nano-biopharmaceutical company which is engaged in discovering, developing, and commercializing therapeutics to advance the care of patients suffering from life-threatening viral infections. The company engaged in the application of nanomedicine technologies to the complex issues of viral diseases. It focuses its research and clinical programs on specific anti-viral therapeutics and is seeking to add to its existing portfolio of products through its internal discovery and clinical development programs and through an in-licensing strategy. Mostrar más

Sector
Pharmaceutical Preparations
Industria
Coml Physical, Biologcl Resh
Sede
Reno, Nevada, USA
Fundado
2005
NanoViricides Inc is listed in the Pharmaceutical Preparations sector of the American Stock Exchange with ticker NNVC. The last closing price for NanoViricides was US$1.68. Over the last year, NanoViricides shares have traded in a share price range of US$ 1.00 to US$ 7.86.

NanoViricides currently has 11,814,000 shares in issue. The market capitalisation of NanoViricides is US$19.85 million. NanoViricides has a price to earnings ratio (PE ratio) of -2.21.

NNVC Últimas noticias

NanoViricides Reports that the Phase I NV-387 Clinical Trial is Completed Successfully and Data Lock is Expected Soon

  SHELTON, CT -- May 2, 2024 -- InvestorsHub NewsWire -- NanoViricides, Inc. (NYSE Amer: NNVC) (the "Company"), a global leader in broad-spectrum antiviral...

Período †Variación(Ptos)Variación %AperturaPrecio MáximoPrecio MínimoAvg. Vol. diarioPrecio Promedio Ponderado
1-0.3-15.70680628271.912.341.523064261.94164716CS
4-0.41-20.2970297032.022.551.522702891.97454196CS
120.4741.22807017541.143.591.02972390622.06982876CS
260.3325.781251.283.5911382411.95174098CS
52-2.26-58.39793281653.877.8613415324.54020913CS
1561.4666.6666666670.2119.80.1757024517.05529189CS
2600001.8000CS

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NNVC Discussion

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everton44 everton44 4 días hace
Fraud alert here, dumping shares for lawsuits
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everton44 everton44 5 días hace
NNVC is basically selling stock to hire lawyers as they are broke. They also hired TOPSTOCKALERTS at stocktwits to false advertise their company to sell these shares. TOPSTOCKALERTS always has members pay for his picks but this one, NNVC was a "free pick" lol. All should be brought up of charges of fraud and theft.
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everton44 everton44 5 días hace
Nice Warning. NNVC a fraud being sued and using TOPstockalerts on stocktwits as their seller of stock
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MiQuant MiQuant 2 semanas hace
WARNING !! ONE of the COMPANIES that developed full spectrum antivirals capable of TOTALLY REPLACING/DISRUPTING NNVC’s candidate products is RedHill Biopharma Ltd. RedHill Biopharma Ltd. (Nasdaq: RDHL), a specialty biopharmaceutical company developing Opaganib (ABC294640) an investigational new drug, not available for commercial distribution. Opaganib has been selected for evaluation by two U.S. government countermeasures programs. Opaganib has demonstrated antiviral activity against SARS-CoV-2, multiple variants, and several other viruses, such as Influenza A and Ebola.

Orally administered sphingosine kinase-2 (SPHK2) selective inhibitor targeting COVID-19, Ebola and other viruses as part of pandemic preparedness. Opaganib's host-directed action is thought to work through the inhibition of multiple pathways, the induction of autophagy and apoptosis, and disruption of viral replication.

Source: https://stkt.co/eaxJhG93
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MiQuant MiQuant 3 semanas hace
The ruling on "Chevron" involved interpretations of laws/rules that contain amiguity. Accroding to the ruling, courts should rely on their own interpretion of ambiguous laws. In the case of the SEC Letter. There is no ambiguity, since its ONLY related to data when SAFETY and EFFICACY do exist in medical/medicines products according to the review panels and scientific guidelines and procedures.
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MiQuant MiQuant 3 semanas hace
THE CONTINUING SAGA OF BIOSCAM NANOVIRICIDES (NNVC)
What is overlooked is the spectrum of this new artificial technology that is ingested/injected into body biologics.
According to the research of the original team that developed the chemical polymeric structures (called nanoviricides, or 'cides) this structures (the nano viricides, a synthetic cell polymeric chemical structures) can cause NEUROTOXICITY or GENOTOXICITY and probably INTERGENERATIONAL GENOTIC DEGENERATIONS (Intergenerational transmission of genetic risk).

// DO your DUE DILLIGENCE //
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loanranger loanranger 3 semanas hace
"afraid to try because that means the drugs might fail and the whole gig would be up" (incomplete quote)
That has been my feeling for a long time. I think the same theory applies to Diwan's former co-worker (who has just left his Company to rot in the Expert Market). In his case, however, he finally put himself out on a limb. A Phase 2 Covid trial failed and he could no longer hide the lack of effectiveness of his candidate.
"In order to determine if NNVC's NV-387 IND package is good enough for FDA, NNVC needs to actually submit it to them."
Too busy doing the hokey-pokey.

JMO....scientifically unqualified.
👍️ 1
loanranger loanranger 3 semanas hace
That's a mistaken belief. And it's not an "alleged" letter.....I posted the link to the exchanged correspondences here:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=174910356
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drkazmd65 drkazmd65 3 semanas hace
I stand corrected - SEC not FDA.

The primary point of my statement remains correct.
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mike41 mike41 3 semanas hace
I'm not an attorney but I believe the Supreme Court ruling on the "Chevron" case makes this alleged SEC letter moot.
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MiQuant MiQuant 3 semanas hace
Yes. It was a SEC Letter. I was clear on that. FDA has no jurisdiction on comuniques done by companies to markets, this is a SEC regulatory field.

The SEC WARNED bioscam company NANOVIRICIDES to ONLY "discuss the objective results of your pre-clinical and clinical trials without concluding that such results demonstrate that your product candidates are safe or effective". Conclusion within the SOLE AUTHORITY of the FDA and comparable foreign regulators.

Note that (nowadays) "comparable regulators" may not be INDIA or CHINA, since quality of data and procedures from foreign countries is being questioned RIGHT NOW by US Congress. Which indeed is a rightful move and things must be corrected before great human life losses befal, just for lack of oversight and the correct application of our western standards.
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loanranger loanranger 3 semanas hace
"So NNVC making official claims that there was no toxicity observed at the tested levels of their drug candidate in public statements is - indeed - something that they should be careful about stating until after FDA review and approval. The FDA emphasized that point in the letter than you cite."

Pretty sure that was an SEC letter, but I'd be very interested to know if the Company has heard directly from the FDA on that score.
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MiQuant MiQuant 3 semanas hace
I would propose that NNVC is MASSIVELY OVERVALUED According to this Peer Analysis via Simply Wallstreet (at market prices as of 08/13/2024) NNVC was valued at 1.9x of book value (BV).

I would argue NANOVIRASCAM is around 0.5x-1.0x BV, which puts the value of NNVC stock at $0.435 - $0.870 per stock.

While other peer companies [i.e BioAffinity, RedHill, Tiempest, Pieris, SAB Biotherapeuitics] that have ALREADY 3 candidate products in Ph1CT (with partners as Seagen, Boston Pharma and Server), and one Co with 2 candidates in Ph2CT and 5 in Ph1CT. These exemplified in particular are valued between 1x and 1.4x of book value as of 08/13/24.

You would have to be insane to pay for NANOVIRASCAM double price at 1.9x of BV. I would argue NANOVIRASCAM is around 0.5x-1.0x BV, which puts the value of NNVC stock at $0.435 - $0.870 per stock.

@Via SimplyWallstreet: NYSEAM:NNVC Stock Report.

// Do your DUE DILLIGENCE //
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MiQuant MiQuant 3 semanas hace
SAFETY HAS NOT BEEN PROVED.

Until, not only all data is reviewed by the FDA, data which can be MANIPULATED, but until Phase 3 Clinical Trials done in a Western Country with standards as high as they should be, show the episodes of ADVERSE EFFECTS, and THERE IS A THOROUGH LONGITUDINAL STUDY of cleareance for NEUROTOXICITY and GENOTOXICITY and INTERGENERATIONAL GENOTIC DEGENERATIONS (Intergenerational transmission of genetic risk).

// Do your DUE DILLIGENCE //
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drkazmd65 drkazmd65 3 semanas hace
And again - you harp on over, and over, and over, and over, and over, and over, with those same partial truths and your projections/assumptions.

Anger is not becoming and is pointless on a message board dude.
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MiQuant MiQuant 3 semanas hace
SAFETY HAS NOT BEEN PROVED.

Until, not only all data is reviewed by the FDA, data which can be MANIPULATED, but until Phase 3 Clinical Trials done in a Western Country with standards as high as they should be, show the episodes of ADVERSE EFFECTS, and THERE IS A THOROUGH LONGITUDINAL STUDY of cleareance for NEUROTOXICITY and GENOTOXICITY and INTERGENERATIONAL GENOTIC DEGENERATIONS (Intergenerational transmission of genetic risk).

// Do your DUE DILLIGENCE //
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MiQuant MiQuant 3 semanas hace
BE CAREFUL.... I can inject you "nanoparticles of cyanide" in a saline solution, without you showing any problems....

NNVC CEO Anil Diwan and accomplices may be playing with saturation of the nanoparticles inside body biologics, as a caviat to current Phase 1-2-3 Clinical Trial Studies protocols, manipulating the legal framework and the FDA.
// Do your DUE DILLIGENCE //
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MiQuant MiQuant 3 semanas hace
You propose a FALUTY LOGIC in EXTREMIS !

SAFETY HAS NOT BEEN PROVED. Until, not only all data is reviewed by the FDA, data which can be MANIPULATED, but until Phase 3 Clinical Trials done in a Western Country with standards as high as they should be, show the episodes of ADVERSE EFFECTS, and THERE IS A THOROUGH LONGITUDINAL STUDY of cleareance for NEUROTOXICITY and GENOTOXICITY and INTERGENERATIONAL GENOTIC DEGENERATIONS (Intergenerational transmission of genetic risk).

BEYOND THAT !!
ANIMAL MODELS are questioned by the scientific literature, for their nearly ZERO merit of PREDICTIVE SAFETY and EFFICACY. For drugs which pass animal tests, 94% will fail during human clinical trials stages (Phases 1 – 3). Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978558/

// Do your DUE DILLIGENCE //.....it seems you have lecture comprehension problems.
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drkazmd65 drkazmd65 3 semanas hace
You remain incorrect - if quite adamant about it.

Assuming that NNVC's CRO/associates did not fudge the data - given an possibility I would not entirely put beyond Diwan or somebody he would hire - there was no toxicity shown in any of the dosing types that were tested in the Phase I trial in India. I met the guy about 9 years ago and he seems smart - but he's slippery in getting a straight answer from.

The fact remains - yes - the FDA hasn't agreed with the results and signed off on them as of yet. The FDA hasn't seen any of the finalized results yet. A technicality at this point, but a significant technicality. And I will agree with you on this point.

So NNVC making official claims that there was no toxicity observed at the tested levels of their drug candidate in public statements is - indeed - something that they should be careful about stating until after FDA review and approval. The FDA emphasized that point in the letter than you cite.

That also doesn't change the fact that - again unless the Indian doctors have lied or Diwan is lying (again a possibility I don't completely rule out) - the drugs have shown no toxicity at the dosing levels that NNVC is recommending. And since the drug candidate has shown no apparent toxicity in their animal model studies to date, there is little reason to think that it's going to start showing significant toxicity in humans vs other mammals.

I DO my due diligence. Perhaps you should be more honest about your motivations here. Harping on, and on, and on, and on, and on,... About the same flippin' nonsense daily gets old dude.

This all is why I want Diwan to pull his head out of his behind and get that data finalized so that the company can get it in front of the FDA and so that the FDA can do its thing.
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MiQuant MiQuant 3 semanas hace
IT DID NOT DEMONSTRATE SAFETY.

There is a SEC LETTER sent to NANOVIRASCAM where it was asked by the regulatory body to drop missleading statements about "SAFETY" and "EFFICACY", of NANOVIRASCAM candidate medicine. There is NO APPROVAL of the results of Phase 1 Clinical Trial in INDIA granted officially by the FDA. I can inject you nanoparticles of "cyanide" in a saline solution, without you showing any problem....

// DO your DUE DILLIGENCE //
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KMBJN KMBJN 3 semanas hace
Yes, I have read your posts, why do you ask?

Just trying to figure out what you were saying, thus the request for clarification.

This is all you really needed to say, "don't believe their PRs or the results."
You didn't really need to do any analysis about MTD or dose being too low or placebo or whatever, since you don't believe any of it anways.

Just need to say "I think they are liars, even though I don't have any evidence or reasoning behind it, other than it smells like a scam."

Glad you made your viewpoint clear. I hope I didn't misstate it. Thanks.
and yes, most small cap biotechs fail. Very risky investments. and potentially high rewards as well. Caution is well-warranted.
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drkazmd65 drkazmd65 3 semanas hace
Yes. That Phase I study did demonstrate safety under the planned dosing schemes. You are incorrect and apparently are not ashamed to let any with intelligence know that you are incorrect.

What that Phase I study did not demonstrate was efficacy in any of the planned dosing schemes against any actual human ailment. That's the problem currently.
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MiQuant MiQuant 3 semanas hace
IT DID NOT DEMONSTRATE SAFETY.

There is a SEC LETTER sent to NANOVIRASCAM where it was asked by the regulatory body to drop missleading statements about "SAFETY" and "EFFICACY", of NANOVIRASCAM candidate medicine. There is NO APPROVAL of the results of Phase 1 Clinical Trial in INDIA granted officialy by the FDA. I can inject you nanoparticles of "cyanide" without you showing any problem....

// DO your DUE DILLIGENCE //
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Kojacky Kojacky 3 semanas hace
Started big position here going over $5
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drkazmd65 drkazmd65 3 semanas hace
What will tell the tale in the end - will Diwan EVER get a Phase II trial launched anywhere? India, China, at one point the old CEO talked about clinical trials to be held in Australia.

The only thing that will move this company up, and up to stay, is a partnership that leads to a successful clinical trail that actually treats sick people. Yes, the Phase I did further demonstrate that the drug is generally safe. But it wasn't used to treat anybody with symptoms of COVID or of anything else.
👍️ 1
MiQuant MiQuant 3 semanas hace
THE CONTINUING SAGA OF BIOSCAM NANOVIRICIDES (NNVC)

As we have seen before, NANOVIRASCAM has faked the Phase 1 CT in INDIA by not curing anyone from any desease or viral infection in its trial. INDIA is one of the most CORRUPT countries on Earth, where you can buy business closings for a price, pay individuals for favors, fake data, and to lie for you, and police are seen in the streets carrying spirits bottles as present for co-option in street corruption. Their helath and medicines regulatory body (CDSCO) has even been engaged in a scheme of quality control abscence whereas children died, news published 14 December 2023, India’s CDSCO medicine regulator is criticised for quality checking only cough medicines destined for export.

This is not particular of INDIA, but even in China Clinical Trials are being questioned right now. US clinical trials in China questioned by US lawmakers, REUTERS 20 August 2024. The International Health Community of regulator bodies and the GOVERNMENT OVERSIGHT from Western Countries must GET TOUGH over THIRD WORLD COUNTRIES CLINICAL TRIALS, and the production of medicines (compounds, etc) and chemicals for the health and food industry.
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sunspotter sunspotter 3 semanas hace
"Did you see the pre-clinical PRs showing efficacy in animal models, better than existing antivirals? or Phase I PRs about safety?"

Yes. Did you read my post at all? It wasn't long.

I'm in the it looks like a scam, it smells like a scam and it walks like a scam camp, and don't believe their PRs or the results claimed by their (conveniently offshore and unreliable) CRO.

FWIW I've yet to be wrong on my diagnosis of similar penny stock schemes.
👍️ 1
MiQuant MiQuant 3 semanas hace
RESEARCH STUDY. NCBI. "Animal testing is used in pharmaceutical and industrial research to predict human toxicity, and yet analysis suggests that animal models are poor predictors of drug safety in humans. The cost of animal research is high—in dollars, delays in drug approval, and in the loss of potentially beneficial drugs for human use.
Human subjects have been harmed in the clinical testing of drugs that were deemed safe by animal studies. Increasingly, investigators are questioning the scientific merit of animal research".
Limitations of Animal Studies for Predicting Toxicity in Clinical Trials. Is it Time to Rethink Our Current Approach? Gail A. Van Norman, MD* Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978558/ (National Center for Biotechnology Information.)
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KMBJN KMBJN 3 semanas hace
Additionally it’s a commonplace in drug development that zero side effects is equivalent to zero efficacy.

Either the results are false, the dose administered was way too low or NV-387 is simply a placebo.

Did you see the pre-clinical PRs showing efficacy in animal models, better than existing antivirals? or Phase I PRs about safety?

Sounds like you are in the "It's fraud. They are lying, but I have no proof" camp.
Or maybe you meant something else by "the results are false?"
I guess anyone can say anything they want without evidence to back it up. See a lot of that here.
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sunspotter sunspotter 3 semanas hace
“ they did seem to show that NV-387 was safe in humans with their Phase I India trial, with NO dose limiting toxicity,”

Failure to establish an MTD (maximally tolerated dose) is not the flex NNVC thinks it is. Regulators want to know the MTD.

Additionally it’s a commonplace in drug development that zero side effects is equivalent to zero efficacy.

Either the results are false, the dose administered was way too low or NV-387 is simply a placebo.

There’s little doubt in my mind that NNVC is yet another penny stock would-be biotech that serves solely as a money making scheme for what passes as its “management”.
👍️ 1
MiQuant MiQuant 3 semanas hace
THE CONTINUING SAGA OF BIOSCAM NANOVIRICIDES (NNVC)

Last novel Phase 1 CT of the nanoparticle was made in INDIA, with ALL HEALTHY INDIVIDUALS and proved nothing (as SEC Letter says), THEY NEVER WERE INFECTED or got ILL with ANY VIRUS. So NANOVIRASCAM did not cure anyone from their Phase 1 CT indian participants in INDIA.

NANOVIRICIDES is under financial stress, CEO has acknowledged in fillings that they may reverse mortgage their company facility. It has only USD $6MM cash to fund survival operations all the while CEO Anyl Diwan and spouse CFO pay themselves (via latest 8-K) USD $44.133,33 monthly (obviousely financed through monthly shares issue dilution), and guess what….

DILUTION
Last April 5th there was an 8-K, with an additional $5MM in shares placed for sale in an “At the Market Offerings” (public primary offering) by Diwan and accomplices. Sales Agent is EF HUTTON who sells, purchase from the Company (or both) of this offering. This “At the Market Offering” could be spread in 12 calendar months, until a full allotment of $50MM is reached under the current Agreement. New 8-K file came out on 08/09/2024. With an additional $9,3MM in shares placed for sale in an “At the Market Offerings”. Totalling now nearly USD $60MM in SHARES DILUTION !! You cannot make this up !!!

NOTE //In January 2020 Diwan and accomplices diluted shares of the company by $8.65MM, in July 2020 Diwan again diluted the company by $11.5MM.

If you assume $2/share for the last placements, whereas, there is no extra-value expected generated from the company by the placement -and since the 2005 warrant convert placements no real value has been created-, then if fair value is the last run rate of shares before May 3rd (in reality is much less) at $1.1, then the dilution into the Market Cap amounts to $1/share, which puts the fair value of the Nanoviricides shares at $0.7 (or less) from fair value prices, after dilution.

A pumping NET then pumps the stock, YOU LOOSE your CASH for a: "false value-for-price stock", Diwan and accomplices gets the CASH FLOWING into his pocket, and pumpers & MOMO trading crowds get DILUTED forever. NANOVIRASCAM ETHERNAL DILUTION
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MiQuant MiQuant 3 semanas hace
Animal testing is used in pharmaceutical and industrial research to predict human toxicity, and yet analysis suggests that animal models are poor predictors of drug safety in humans. The cost of animal research is high—in dollars, delays in drug approval, and in the loss of potentially beneficial drugs for human use.

Human subjects have been harmed in the clinical testing of drugs that were deemed safe by animal studies. Increasingly, investigators are questioning the scientific merit of animal research. Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978558/
👍️0
MiQuant MiQuant 3 semanas hace
Nanoviricides published a PR note indicating “protection” in an animal model for lung damage in mice infected with H3N2 avian flu, one of the the current flu strains that epidemiologists are monitoring.

What investors and MOMO retail traders do not grasp is that: The first thing to note is of those drugs which pass animal tests, 94% will fail during human clinical trials stages (Phases 1 – 3)* Source: https://www.animalresearch.info/en/medical-advances/articles-lectures/nine-out-of-ten-statistics-are-taken-out-of-context
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KMBJN KMBJN 3 semanas hace
What is overlooked is the spectrum of this new artificial technology that is ingested/injcted into body biologics. According to the research of the original team that developed the chemical polymeric structures (called nanoviricides, or 'cides) this structures (the nano viricides, a synthetic cell polymeric chemical structures) can cause NEUROTOXICITY or GENOTOXICITY.

Can you please tell us where to find this information, on your claim that the nanoviricides are toxic to neurons and to the genome? Appreciate you sharing, and your tales of caution.
👍️0
MiQuant MiQuant 4 semanas hace
What is overlooked is the spectrum of this new artificial technology that is ingested/injcted into body biologics. According to the research of the original team that developed the chemical polymeric structures (called nanoviricides, or 'cides) this structures (the nano viricides, a synthetic cell polymeric chemical structures) can cause NEUROTOXICITY or GENOTOXICITY.

There is a clear failure of the current protocols to measure the "effectivenes" of this nano structures in the time frame of Phase 1-2-3 Clinical Trial protocols rushed by IND's that mark effiency in reduced time periods. Anil Diwan and accomplices will micro manage the dose, so that these two kinds of toxicity do not register into YOUR BODY BIOLOGICS for some time (at least throughout the duration of the Clinical Trials), but later human life cicle effects could envision NEUROTOXICIRY, GENOTIXICITY and INTERGENERATIONAL GENOTIC DEGENERATIONS (Intergenerational transmission of genetic risk).

The situation in India is hence, UNCLEAR, since if we pay any respect to science, the time to measure NANOTIXICITY or GENOTOXICITY is only achieved with LONGITUDINAL STUDIES in great numbers of population after at least a DECADE (to say the least). Intergenerational genotic risk MUST be in the CONTROL VARIABLES.

The company may be playing with micro (nano) accumulation and sizes, introduced in body biologics, so that it doesen’t register toxicity for some years, as a caviat to current Phase 1-2-3 Clinical Trial Studies protocols, manipulating the legal framework and the FDA.

These are nano particles alien to body biologics that may develop neurotoxicity or genotoxicity. Only with broad (and long time -i.e decades long) longitudinal studies that are run for 10 years plus, one could really determine if these nano structures are safe for body biologics.
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KMBJN KMBJN 4 semanas hace
In order to determine if NNVC's NV-387 IND package is good enough for FDA, NNVC needs to actually submit it to them. It remains puzzling why NNVC goes so slowly with FDA and clinical trials, other than that Diwan is a cowardly and greedy control freak (loves the gravy train, afraid to try because that means the drugs might fail and the whole gig would be up), or maybe they are still working out some manufacturing issues, or there is some other unknown reason why it has taken them so long to apply for an IND and take one of their many 'cides into trials in the US after all these years. If I recall correctly, the last communication was that NNVC was going to have a pre-IND meeting, and think about submitting an IND for NV-387 by the end of 2025. They are hoping their NV-387 that targets HSPG binding viral antigens will be an oral, broad spectrum antiviral, good against multiple (respiratory) viruses like RSV, CoV, and IAV (fluA). It's WAY WAY overdue for them to plan and get into a human trial. They move SO SLOWLY that it is bewildering. That said, they did seem to show that NV-387 was safe in humans with their Phase I India trial, with NO dose limiting toxicity, and this data will surely be part of their IND submission to FDA, along with their planned Phase II trial against multiple respiratory viruses. People can and will continue to shout fraud here, without presenting any solid evidence of said fraud. Hard to know what to believe. The truth will come out some day. That day keeps getting closer and closer as NNVC finally does a trial to see if these nanomedicines work, or they run out of money, or something. It will be interesting to see if they can get a partner to fund and run the trial.
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MiQuant MiQuant 4 semanas hace
There is a reason why the indian CEO of NANOVIRASCAM, Anil Diwan, makes the Clinical Trials in INDIA. INDIA is one of the most CORRUPTED countries on earth. This makes it easy to "buy" results in Clinical Trials, and hide adverse cases and/or geno/neuro-toxicity from the nano particles (aka nanoviricides).

India’s CDSCO medicine regulator is criticised for quality checking only cough medicines destined for export
(Published 14 December 2023) News LINK: https://www.bmj.com/content/383/bmj.p2951


Kamala Thiagarajan

India’s system for regulating medicines has been questioned after an investigation found that more than 100 cough syrups made for the export market failed quality tests.

Specialists have said that the Central Drugs Standard Control Organization (CDSCO), the national regulatory body for pharmaceuticals that conducted the investigation, lacks the necessary oversight to ensure that medicines manufactured in India are safe.

The comments follow a report from CDSCO shared with the media on 4 December on the results of tests conducted on more than 2000 cough syrups. Of these, 128 syrups manufactured by 54 companies, which were meant for the export market, were found to have problems with quality.

In June this year India’s director general of foreign trade mandated that cough syrups meant for export must undergo tests at a government laboratory and must be authorised with a certificate of analysis before they can leave the country. However, Dinesh Thakur, a public health activist and coauthor of a book about drug regulation in India, questioned why the policy was limited to just one type of medicine.

“Clearly, the outrage associated with the deaths of the children has resulted in this action, but this only applies to cough syrups,” he told The BMJ. “If this is the case with one class of medicinal product, what about the rest?” He added that it was not clear whether companies found to be in breach of standards would face any consequences.
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loanranger loanranger 4 semanas hace
"The very fact that a reputable regulatory body such as CDSCO allowed us to enter into a clinical trial is indicative that the drug candidate was deemed to be sufficiently safe and effective for humans."
Didn't the FDA say "If it's good enough for Central Drugs Standard Control Organization (“CDSCO”), a regulatory body in India, it's good enough for us?"

I didn't think so.
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KMBJN KMBJN 4 semanas hace
What do you mean we can't say our 'cides are "safe" and "effective" ?!?

Ummm, OK, you are the SEC I guess. We'll just talk about the "strong effectiveness parameters" of NV-387, then :).

https://finance.yahoo.com/news/nanoviricides-continues-march-towards-phase-103000857.html

"NanoViricides Continues Its March ..." a long, twisted, 20 year march, which may lead to a trial filing in the US in 2025.

Wouldn't that be amazing if these things really work as well in humans as they did in animals?
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glenn1919 glenn1919 4 semanas hace
NNVC..................................https://stockcharts.com/h-sc/ui?s=NNVC&p=W&b=5&g=0&id=p86431144783
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sunspotter sunspotter 1 mes hace
Next step is probably a Wells Notice.
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loanranger loanranger 1 mes hace
The SEC had some questions about last year's 10-K and the Qs and As have been posted to Edgar. Several go to the TheraCour relationship and the use of the terms "safe" and "effective" in that filing.
https://www.sec.gov/Archives/edgar/data/1379006/000000000024001724/filename1.pdf
https://www.sec.gov/Archives/edgar/data/1379006/000110465924045423/filename1.htm
https://www.sec.gov/Archives/edgar/data/1379006/000000000024004397/filename1.pdf
https://www.sec.gov/Archives/edgar/data/1379006/000110465924058925/filename1.htm
https://www.sec.gov/Archives/edgar/data/1379006/000000000024005448/filename1.pdf
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loanranger loanranger 1 mes hace
Contract extensions aren't hard to get if you know the right people:
https://www.sec.gov/Archives/edgar/data/1379006/000110465924087828/0001104659-24-087828-index.htm
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loanranger loanranger 1 mes hace
Butbutbut "Together, just the three viruses, Influenza, RSV, and COVID, account for over $8 Billion in estimated market size in 2024, growing to an estimated $12 Billion in three years, as calculated by us from various market reports.".

Cue Carl Sagan......
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drkazmd65 drkazmd65 1 mes hace
From today's cheesy PR - Diwan has pushed back the goalposts yet again,.... end of Calendar Year 2025?

Simultaneously, we are preparing for a Phase II clinical trial with the objective of evaluation of effectiveness of NV-387 as an antiviral in humans. We have initiated the required non-clinical GLP animal studies already, and anticipate the reports on these studies by the end of CY 2025.
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loanranger loanranger 1 mes hace
Probably reminds you of every other shady drug developer CEO on the planet. Can't swing a dead cat.........
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sunspotter sunspotter 1 mes hace
“ Diwan loves those "Market X is expected to reach USD Y Bn by 20ZZ" lines.”

Now of whom does that remind me?
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loanranger loanranger 1 mes hace
"The Global Antiviral Drugs Market is estimated to reach USD 74.75 Bn by 2028" and I'll bet NNVC will still be looking for its first dollar of that at that time.

Diwan loves those "Market X is expected to reach USD Y Bn by 20ZZ" lines. He's good for at least a couple of them a year.
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drkazmd65 drkazmd65 1 mes hace
Yet another 'paid for' pump by Diwan,..... How about actually lining up a partner Mr. CEO?

https://www.investorideas.com/News/2024/nanotech/08020Better-Solutions-for-Viruses.asp#google_vignette
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loanranger loanranger 2 meses hace
I'll bet there's a good reason. It's just not obvious. Pumperooski? Every time this happens it finds its way back down.
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