RNS Number:7060I
Bioscience Inv Trust PLC
16 February 2005


                                                                16 February 2005

                    Substantial Share Interest Notification


We are writing to advise that the Company was notified on 16 February 2005, that
Citigroup Global Markets UK Equity Limited has a notifiable interest in
1,930,000 ordinary shares, representing 4.316% of the 44,715,844 shares in
issue.


Enquiries:

 John Spedding
 Schroder Investment Management Limited                  Tel: 020 7658 3206



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            The company news service from the London Stock Exchange
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