Oxford Nanopore Technologies plc Nanopore Community Meeting Technology Update (0790W)
07 Diciembre 2023 - 10:30AM
UK Regulatory
TIDMONT
RNS Number : 0790W
Oxford Nanopore Technologies plc
07 December 2023
Oxford Nanopore Technologies plc
Nanopore Community Meeting Technology Update
7 December 2023
Oxford Nanopore Technologies plc (LSE: ONT) ("Oxford Nanopore"),
the company delivering a new generation of nanopore-based molecular
sensing technology, on Wednesday announced an R&D programme
delivering a significant jump in platform performance to enable
further scientific discovery, in addition to a springboard into
clinical markets, as part of a broader technology update at its
Nanopore Community Meeting in Houston.
Oxford Nanopore SVP of Product and Programme Management Rosemary
Sinclair Dokos and SVP R&D Biologics Lakmal Jayasinghe detailed
breakthrough performance in DNA/RNA nanopore sequencing, including
new improvements in DNA sequencing accuracy - reaching a record of
Q28 (99.8%) in median simplex single pass accuracy - powered by
machine learning-guided enzyme engineering and improved models.
They also detailed a novel method to overcome errors in homopolymer
regions that, when combined with other platform updates, pushed
human consensus accuracy up to Q50 and indel F1 accuracy to
99%.
Additional platform updates included significant improvements in
direct RNA sequencing to support the emergence of RNA-based
therapies as well as numerous research areas of RNA biology,
including m6A modified base calling.
As Oxford Nanopore continues to expand its user community in
clinical and industrial applied markets, the team also shared the
latest on its locked down product platform, Q-line, and announced
TurBOT beta access to deliver an optimised sample-to-result
product, strengthening its collaboration with Tecan.
A replay of the presentation is available to view on the Oxford
Nanopore website at:
https://nanoporetech.com/about-us/news/oxford-nanopore-announces-breakthrough-performance-simplex-single-molecule-accuracy
-ENDS-
For further information, please contact:
Oxford Nanopore Technologies plc
Investors: ir@nanoporetech.com
Media: media@nanoporetech.com
Teneo (communications adviser to the Company)
Tom Murray, Olivia Peters
+44 (0) 20 7353 4200
OxfordNanoporeTechnologies@teneo.com
About Oxford Nanopore Technologies plc:
Oxford Nanopore Technologies' goal is to bring the widest
benefits to society through enabling the analysis of anything, by
anyone, anywhere. The company has developed a new generation of
nanopore-based sensing technology that is currently used for
real-time, high-performance, accessible, and scalable analysis of
DNA and RNA. The technology is used in more than 120 countries, to
understand the biology of humans, plants, animals, bacteria,
viruses and environments as well as to understand diseases such as
cancer. Oxford Nanopore's technology also has the potential to
provide broad, high impact, rapid insights in a number of areas
including healthcare, food and agriculture.
For more information please visit: www.nanoporetech.com
Forward-looking statements
This announcement contains certain forward-looking statements.
For example, statements regarding expected revenue growth and
profit margins are forward-looking statements. Phrases such as
"aim", "plan", "expect", "intend", "anticipate", "believe",
"estimate", "target", and similar expressions of a future or
forward-looking nature should also be considered forward-looking
statements. Forward-looking statements address our expected future
business and financial performance and financial condition, and by
definition address matters that are, to different degrees,
uncertain. Our results could be affected by macroeconomic
conditions, the COVID-19 pandemic, delays in our receipt of
components or our delivery of products to our customers,
suspensions of large projects and/or acceleration of large products
or accelerated adoption of pathogen surveillance. These or other
uncertainties may cause our actual future results to be materially
different than those expressed in our forward-looking
statements.
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