MabCure Signs a Collaboration Agreement with a Leading Medical Center in Europe for a Study Aimed at Further Development of a...
19 Octubre 2010 - 8:00AM
Business Wire
Biotechnology company MabCure, Inc. (OTCBB: MBCI) today
announced that it has signed a collaboration agreement with
Catholic University, K.U. Leuven and University Hospital, UZ
Leuven, Belgium, together comprising one of the largest and most
reputable medical centers in Europe.
The agreement reflects the parties’ continued interest in
exploring the utility of MabCure’s diagnostic test for ovarian
cancer and will assist MabCure in advancing its clinical program.
This collaboration follows MabCure’s joint study with Professor
Ignace Vergote, a world renowned authority on ovarian cancer, which
provided a proof of concept for the ability of MabCure’s antibodies
to distinguish between ovarian cancer and benign tumors.
In that study, several of MabCure’s ovarian cancer monoclonal
antibodies (MAbs) were tested against 54 different blood samples
comprised of 17 patients with ovarian cancer, 5 patients with
benign tumors of the ovaries, 24 healthy young females and 8 males.
Each of the company's proprietary MAbs successfully identified
ovarian cancer in blood with 94 percent accuracy (i.e. correctly
identifying 16 of 17 patients as having ovarian cancer) and with no
false positives or cross-reactions with benign ovarian tumors or
healthy blood.
The new collaboration is aimed at expanding MabCure’s diagnostic
database in order to pave the way to multi-center clinical studies
in Europe and the United States.
Professor Ignace Vergote serves as Chairman of the
Multidiciplinary Department of Gynecologic Oncology, University
Hospital Leuven, Belgium and Professor of Gynecologic Oncology,
Catholic University Leuven, Belgium. From 1997 to 2003 Professor
Vergote served as the Chairman of the European Organization for
Research and Treatment of Cancer (EORTC), Gynecologic Cancer Group,
and is currently the Chairman of the Protocol committee of that
group.
Dr. Amnon Gonenne, CEO of MabCure, noted: “we are privileged to
form such an important alliance with Professor Vergote and the
University Hospital, UZ Leuven. Professor Vergote’s vast knowledge
and reputation in the field of gynecological cancers will be
invaluable in assisting MabCure during our clinical trials of
ovarian cancer and ultimately in reaching a broad network of
medical centers in Europe and the U.S.”
About Ovarian Cancer
Each year, 230,000 women worldwide are diagnosed with ovarian
cancer, or cancer that forms in the tissues of the ovary,
accounting for three percent of cancers in women. More than 125,000
women die from ovarian cancer annually, making it the fifth leading
cause of cancer death in women and the deadliest of all
gynecological cancers.
About MabCure’s Technology
MabCure has re-engineered classic hybridoma technology. Classic
hybridoma technology is based on the generation of immortal hybrid
cells or hybridoma, which follows the fusion of antibody-producing
B-cells with myeloma tumor cells. Each hybridoma continuously
manufactures a single monoclonal antibody. MabCure’s enhanced
technology has improved upon this process by increasing MAb yield,
improving production times exponentially, and enhancing
specificity.
MabCure has successfully generated several highly specific
monoclonal antibodies against four different cancers - ovarian
cancer, an aggressive form of prostate cancer, colon carcinoma and
melanoma. Each of these antibodies has been shown to be "universal"
to each type of cancer, i.e. they recognize cancer cells or
antigens from different individuals having that particular disease
but do not recognize other cancers or normal antigen tested so far.
These MAbs are the first candidates for the development of novel
diagnostic tools, imaging agents and drugs to treat the
corresponding cancers.
About MabCure
MabCure is a U.S. biotechnology company whose mission is to
change the perception of cancer as being a largely incurable
disease. MabCure owns proprietary technology for the creation of
unique and highly specific monoclonal antibodies (MAbs), which the
company plans to develop as diagnostic tools, imaging agents and
therapeutic drugs to treat lethal cancers. The company’s initial
focus is on the development of novel diagnostic tests for the early
detection of ovarian, prostate, and colorectal cancers, each with
multi-billion dollar global market potential. MabCure is also
currently exploring the potential of its anti-melanoma antibodies
for the development of imaging and therapeutic agents. The company
is headquartered in Hasselt, Belgium. For more information about
MabCure and to sign up for e-mail updates, visit
www.mabcure.com.
This news release contains “forward-looking statements.”
Statements in this news release which are not purely historical are
forward-looking statements and include any statements regarding
beliefs, plans, expectations or intentions regarding the future.
Actual results could differ from those projected in any
forward-looking statements due to numerous factors. Such factors
include, among others, the change of business focus of the
management of the Company and the inability of the Company to
pursue its current objectives. These forward-looking statements are
made as of the date of this news release and the Company assumes no
obligation to update the forward-looking statements, or to update
the reasons why actual results could differ from those projected in
the forward-looking statements.
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