FORM 4
[ X ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

BESBECK STEVEN M 		2. Issuer Name and Ticker or Trading Symbol

IRIS INTERNATIONAL INC [ IRIS ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__ X __ Director                      _____ 10% Owner
_____ Officer (give title below)      _____ Other (specify below)
(Last)          (First)          (Middle)

C/O IRIS INTERNATIONAL, INC., 9158 ETON AVENUE 		3. Date of Earliest Transaction (MM/DD/YYYY)

10/31/2012
(Street)

CHATSWORTH, CA 91311
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock   10/31/2012     U    40537   D $19.50   0   D    
Common Stock   10/31/2012     M    13043   A $16.89   13043   D    
Common Stock   10/31/2012     M    13888   A $10.07   26931   D    
Common Stock   10/31/2012     M    12541   A $11.61   39472   D    
Common Stock   10/31/2012     M    2414   A $13.26   41886   D    
Common Stock   10/31/2012     F (1)    27578   D $19.50   14308   D    
Common Stock   10/31/2012     S (2)    14308   D $19.50   0   D    

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy)   $16.89   10/31/2012     M         13043      (3) 7/13/2018   Common Stock   13043   $0   0   D    
Stock Option (Right to Buy)   $10.07   10/31/2012     M         13888      (4) 5/22/2019   Common Stock   13888   $0   0   D    
Stock Option (Right to Buy)   $11.61   10/31/2012     M         12541      (5) 5/14/2020   Common Stock   12541   $0   0   D    
Stock Option (Right to Buy)   $13.26   10/31/2012     M         2414      (6) 4/27/2019   Common Stock   2414   $0   7245   D    
Stock Option (Right to Buy)   $13.26   10/31/2012     D         7245      (7) 4/27/2019   Common Stock   7245   $6.24   0   D    
Restricted Stock Units     (8) 10/31/2012     D         2828      (9)   (9) Common Stock   2828   $19.50   0   D    

Explanation of Responses:
( 1)  The shares were retained by the company in payment of the exercise price incurred in connection with the exercise of options.
( 2)  Pursuant to a Tender and Support Agreement dated September 17, 2012 by and among each director and officer of IRIS International, Inc., IRIS International, Inc., Danaher Corporation and Daphne Acquisition Corporation, the reporting person sold these shares of Common Stock to Daphne Acquisition Corporation in exchange for consideration of $19.50 per share.
( 3)  Vested and became exercisable in equal quarterly installments of 25% each on September 13, 2008, December 13, 2008, Mach 13, 2009 and June 13, 2009.
( 4)  The stock options vested in three equal installments on each of November 22, 2009, February 22, 2010 and May 22, 2010.
( 5)  The stock options vested in three equal installments on each of November 14, 2010, February 14, 2011 and May 14, 2011.
( 6)  Vested / will vest 25% on each of July 31, 2012, October 31, 2012, January 31, 2013 and April 30, 2013.
( 7)  Pursuant to the Agreement and Plan of Merger dated September 17, 2012 by and among Danaher Corporation, Daphne Acquisition Corporation and IRIS International, Inc. (the "Merger Agreement"), this option vested in full and was cancelled in the merger in exchange for a cash amount equal to the number of shares underlying this option multiplied by the difference between the per share merger consideration of $19.50 and the per share exercise price of this option.
( 8)  Each restricted stock unit represents a contingent right to receive one share of IRIS International, Inc. common stock.
( 9)  Pursuant to the Merger Agreement, these restricted stock units vested in full and were cancelled in the merger in exchange for a cash amount equal to the number of shares underlying the restricted stock units multiplied by the per share merger consideration of $19.50.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
BESBECK STEVEN M
C/O IRIS INTERNATIONAL, INC.
9158 ETON AVENUE
CHATSWORTH, CA 91311 		X



Signatures
/s/ Todd M. Graham, Attorney-in-Fact 11/1/2012
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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