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CUSIP NO. 896263100 13G Page 2 of 8 Pages
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(1) NAMES OF REPORTING PERSONS.
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (entities only).
Renaissance Technologies LLC 26-0385758
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(2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS):
(a) [_]
(b) [_]
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(3) SEC USE ONLY
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(4) CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
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(5) SOLE VOTING POWER
NUMBER OF SHARES 1,275,000
BENEFICIALLY OWNED _____________________________
BY EACH REPORTING
PERSON WITH: (6) SHARED VOTING POWER
0
_____________________________
(7) SOLE DISPOSITIVE POWER
1,275,000
_____________________________
(8) SHARED DISPOSITIVE POWER
0
______________________________
(9) AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,275,000
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(10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
(SEE INSTRUCTIONS)
[_]
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(11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
5.7%
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(12) TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
IA
Page 2 of 8 pages
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CUSIP NO. 896263100 13G Page 3 of 8 Pages
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(1) NAMES OF REPORTING PERSONS.
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).
James H. Simons
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(2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) [_]
(b) [_]
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(3) SEC USE ONLY
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(4) CITIZENSHIP OR PLACE OF ORGANIZATION
United States
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(5) SOLE VOTING POWER
NUMBER OF SHARES 0
BENEFICIALLY OWNED _____________________________
BY EACH REPORTING
PERSON WITH: (6) SHARED VOTING POWER
0
_____________________________
(7) SOLE DISPOSITIVE POWER
0
_____________________________
(8) SHARED DISPOSITIVE POWER
0
_____________________________
(9) AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
0
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(10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
(SEE INSTRUCTIONS)
[_]
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(11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
0
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(12) TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
OO
Page 3 of 8 pages
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CUSIP NO. 896263100 13G Page 3 of 8 Pages
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(1) NAMES OF REPORTING PERSONS.
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).
RENAISSANCE TECHNOLOGIES HOLDINGS CORPORATION 13-3127734
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(2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) [_]
(b) [_]
-----------------------------------------------------------------------------
(3) SEC USE ONLY
-----------------------------------------------------------------------------
(4) CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
-----------------------------------------------------------------------------
(5) SOLE VOTING POWER
NUMBER OF SHARES 1,275,000
BENEFICIALLY OWNED _____________________________
BY EACH REPORTING
PERSON WITH: (6) SHARED VOTING POWER
0
_____________________________
(7) SOLE DISPOSITIVE POWER
1,275,000
_____________________________
(8) SHARED DISPOSITIVE POWER
0
_____________________________
(9) AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,275,000
-----------------------------------------------------------------------------
(10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
(SEE INSTRUCTIONS)
[_]
-----------------------------------------------------------------------------
(11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
5.7 %
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(12) TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
HC
Page 3 of 8 pages
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CUSIP NO. 896263100 13G Page 4 of 8 Pages
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Item 1.
(a) Name of Issuer
TRIMERIS, INC
(b) Address of Issuer's Principal Executive Offices.
2530 Meridian Parkway, 2nd Floor, Durham, North Carolina 27713
Item 2.
(a) Name of Person Filing:
This Schedule 13G is being filed by Renaissance Technologies LLC
("RTC"), James H. Simons ("Simons") and Renaissance Technologies Holdings
Corporation ("RTHC").
(b) Address of Principal Business Office or, if none, Residence.
The principal business address of the reporting persons is:
800 Third Avenue
New York, New York 10022
(c) Citizenship.
Dr. Simons is a United States citizen,
RTC is a Delaware limited liability company, and
RTHC is a Delaware corporation.
(d) Title of Class of Securities.
common stock
(e) CUSIP Number.
896263100
Page 4 of 8 pages
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Item 3. If this statement is filed pursuant to Rule 13d-1(b) or 13-d-2(b)
or (c),check whether the person filing is a:
(a) [_] Broker or dealer registered under section 15 of the Act.
(b) [_] Bank as defined in section 3(a)(6) of the Act.
(c) [_] Insurance Company as defined in section 3(a)(19) of the Act.
(d) [_] Investment Company registered under section 8 of the Investment
Company Act.
(e) [x] Investment Adviser in accordance with Sec.240.13d-1(b)(1)(ii)(E).
(f) [_] Employee Benefit Plan or Endowment Fund in accordance with
Sec. 240.13d-1(b)(1)(ii)(F).
(g) [_] Parent holding company, in accordance with Sec.240.13d-1(b)(1)(ii)(G).
(h) [_] A savings associations as defined in Section 3(b) of the Federal
Deposit Insurance Act.
(i) [_] A church plan that is excluded from the definition of an investment
company under section 3(c)(14) of the Investment Company Act of 1940.
(j) [_] Group, in accordance with Sec.240.13d-1(b)(1)(ii)(J).
Item 4. Ownership.
(a) Amount beneficially owned.
RTC: 1,275,000 shares
Simons: 0 shares, because Dr. Simons is no longer deemed to be a control
person of RTC.
RTHC: 1,275,000 shares, comprising the shares beneficially owned
by RTHC, because of RTHC's majority ownership of RTC.
(b) Percent of Class.
RTC: 5.7 %
Simons: 0 %
RTHC: 5.7 %
(c) Number of shares as to which the person has:
(i) sole power to vote or to direct the vote:
RTC: 1,275,000
Simons: 0
RTHC: 1,275,000
(ii) Shared power to vote or to direct the vote: 0
(iii) sole power to dispose or to direct the disposition of:
RTC: 1,275,000
Simons: 0
RTHC: 1,275,000
(iv) Shared power to dispose or to direct the disposition of:
RTC: 0
Simons: 0
RTHC: 0
Page 5 of 8 pages
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Item 5. Ownership of Five Percent or Less of a Class.
If this statement is being filed to report the fact that as of the
date hereof the reporting person has ceased to be the beneficial
owner of more than five percent of the class of securities,
check the following: [_]*
*As of January 1, 2010, James H. Simons ceased to be the beneficial owner of
any of the securities reported herein.
Item 6. Ownership of More than Five Percent on Behalf of Another Person.
Certain funds and accounts managed by RTC have the right to receive
dividends and proceeds from the sale of the securities which are
the subject of this report.
Item 7. Identification and Classification of the Subsidiary Which Acquired
the Security Being Reported on by the Parent Holding Company.
Not applicable
Item 8. Identification and Classification of Members of the Group.
Not applicable
Item 9. Notice of Dissolution of a Group.
Not applicable
Page 6 of 8 pages
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Item 10. Certification
By signing below I certify that, to the best of my knowledge and belief,
the securities referred to above were acquired and are held in the ordinary
course of business and not acquired and are not held for the purpose of or
with the effect of changing or influencing the control of the issuer of the
securities and were not acquired and are not held in connection with or as
a participant in any transaction having that purpose or effect.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete
and correct.
Date: February 11, 2011
Renaissance Technologies LLC
By: Mark Silber
Executive Vice President
James H. Simons
Renaissance Technologies Holdings Corporation
By: Mark Silber
Vice President
Attention: Intentional misstatements or omissions of fact constitute
Federal criminal violations (See 18 U.S.C. 1001).
Page 7 of 8 Pages
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EXHIBIT 99.1
AGREEMENT REGARDING JOINT FILING
UNDER RULE 13D-1(K) OF THE EXCHANGE ACT
In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934,
as amended, each of the undersigned agrees to the filing on behalf of each
of a Statement on Schedule 13G, and all amendments thereto, with respect to
the shares of common stock of
TRIMERIS, INC.
Date: February 11, 2011
Renaissance Technologies LLC
By: Mark Silber
Executive Vice President
James H. Simons
Renaissance Technologies Holdings Corporation
By: Mark Silber
Vice President
Page 8 of 8 Pages
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