RNS Number:7733L
Skyepharma PLC
2 June 2003


For Immediate Release                                               2 June 2003



SkyePharma PLC



Notification of Interests of Directors



The Company was informed on 30 May 2003 by Mr Ian Gowrie-Smith, Executive
Chairman of SkyePharma PLC, that on 30th May 2003 6,000,000 Ordinary Shares from
his beneficial holding in the Company had been sold at a price of 53 pence per
share to meet part of the obligations previously referred to in the Directors'
Interests section of the Company's Annual Report.  As a result of the
transaction Mr Gowrie-Smith now has a beneficial interest in 19.3 million
Ordinary Shares in the Company (subject to the proposed transfer previously
disclosed in the Annual Report).



ends


SkyePharma Plc                                             + 44 (0) 20 7491 1777

Peter Laing, Director of Corporate Communications

US Investor Relations                                         + 1 (212) 753-5780
Sandra Haughton

Buchanan Communications                                     +44 (0) 20 7466 5000
Tim Anderson / Nicola How




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