Evotec and X-Chem Collaborate to Accelerate Early-Stage Drug Discovery
05 Septiembre 2024 - 7:00AM
Business Wire
Evotec SE (Frankfurt Stock Exchange: EVT, MDAX/TecDAX, ISIN:
DE0005664809; NASDAQ: EVO) and X-Chem, leader in DNA-encoded
library (DEL) technology, today announced a collaboration agreement
focused on accelerating early-stage drug discovery.
X-Chem’s DEL technology streamlines hit finding by
simultaneously screening up to billions of DNA-tagged compounds,
identifying potential start points with high efficiency and
precision.
In partnership with Evotec’s screening platforms and
capabilities, X-Chem is providing access to its DEL technology,
including DELflex, a traditional experimental DEL solution, and
HITMiner, a machine learning solution, leveraging high quality
experimental DEL data to deliver optimal drug intervention starting
points for innovative biological targets.
“Partnerships to access best-in-class platforms are the way
forward to address the complexity in drug discovery,” said Karen
Lackey, CEO of X-Chem. “This collaboration highlights our
commitment to partner with leading research organizations, like
Evotec, to make DEL screening services more accessible.”
“We are pleased to collaborate with X-Chem and to leverage their
leading DEL platform and capabilities,” said Craig Johnstone, chief
operating officer of Evotec. “X-Chem’s expertise in DEL, combined
with their advanced data-mining solutions, provides us with access
to an additional tool to tackle innovative and difficult biological
targets.”
About X-Chem
X-Chem, Inc. is a leader in small molecule discovery science,
providing pharmaceutical and biotechnology companies with a
complete, seamless solution for screening, hit validation and lead
optimization. As pioneers of DNA-encoded chemical library (DEL)
technology, the company leverages its market-leading DEL platform
to rapidly screen billions of diverse drug-like molecules to
discover novel small molecule leads against challenging, high-value
therapeutic targets. In house hit-to-lead and lead optimization
services driven by AI and physics-based modeling enable clients to
progress their compounds directly in-house from hit all the way
through to candidate nomination. Our well-proven expertise in
medicinal chemistry, custom synthesis and scale-up process
chemistry enables us to support all aspects of drug discovery in a
deeply integrated technology-driven platform.
About Evotec SE
Evotec is a life science company with a unique business model
that delivers on its mission to discover and develop highly
effective therapeutics and make them available to the patients. The
Company’s multimodality platform comprises a unique combination of
innovative technologies, data and science for the discovery,
development, and production of first-in-class and best-in-class
pharmaceutical products. Evotec provides high value pipeline
co-creating partnerships and solutions to all Top 20 Pharma and
over 800 biotechnology companies, academic institutions, as well as
other healthcare stakeholders. Evotec has strategic activities in a
broad range of currently underserved therapeutic areas, including
e.g. neurology, oncology, as well as metabolic and infectious
diseases. Within these areas of expertise, Evotec aims to create
the world-leading co-owned pipeline for innovative therapeutics and
has to-date established a portfolio of more than 200 proprietary
and co-owned R&D projects from early discovery to clinical
development. Evotec operates globally with more than 5,000 highly
qualified people. The Company’s sites in Europe and the USA offer
highly synergistic technologies and services and operate as
complementary clusters of excellence. For additional information
please go to www.evotec.com.
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