Filed pursuant to Rule 424(b)(5)
Reg. Statement No. 333-269994
PROSPECTUS SUPPLEMENT
(To prospectus dated
February 24, 2023)
Sunstone Hotel Investors, Inc.
$300,000,000
Common
Stock
We have entered into a joint equity distribution agreement, dated as of March 1, 2023, with each of BofA Securities, Inc., BTIG, LLC,
Jefferies LLC, J.P. Morgan Securities LLC, Regions Securities LLC, Robert W. Baird & Co. Incorporated, Scotia Capital (USA) Inc., Truist Securities, Inc. and Wells Fargo Securities, LLC, each a sales agent and, collectively, the sales
agents, and, if applicable, the relevant forward purchasers (as defined below), relating to the offer and sale of shares of common stock, $0.01 par value per share, or common stock, having an aggregate offering price of up to $300,000,000, to be
made from time to time under this prospectus supplement and the accompanying prospectus through the sales agents, as our sales agents or, if applicable, as forward sellers (as defined below), or directly to the sales agents as principals for their
own accounts. Upon entry into the equity distribution agreement, we terminated our prior at-the-market program. At the time of such termination, shares of common stock
having an aggregate gross sales price of up to $137,024,610 remained unsold under such prior program.
The equity distribution agreement
contemplates that, in addition to the issuance and sale by us of shares of our common stock to or through the sales agents, we may enter into separate forward sale agreements with each of Bank of America, N.A., Jefferies LLC, JPMorgan Chase Bank,
National Association, Regions Securities LLC, Robert W. Baird & Co. Incorporated, The Bank of Nova Scotia, Truist Bank and Wells Fargo Bank, National Association, or one of their respective affiliates (in such capacity, each a forward
purchaser and, collectively, the forward purchasers). If we enter into a forward sale agreement with any forward purchaser, we expect that such forward purchaser (or its affiliate) will use its commercially reasonable efforts to borrow from third
parties and the relevant sales agent will use commercially reasonable efforts consistent with its normal trading and sales practices to sell, through the relevant sales agent, as forward seller, shares of our common stock to hedge such forward
purchasers exposure under such forward sale agreement. We refer to a sales agent, when acting as sales agent for the relevant forward purchaser, as, individually, a forward seller and, collectively, the forward sellers. Unless otherwise
expressly stated or the context otherwise requires, references herein to the related or relevant forward purchaser mean, with respect to any sales agent, the affiliate of such sales agent that is acting as forward purchaser
or, if applicable, such sales agent acting in its capacity as forward purchaser. We will not initially receive any proceeds from any sale of shares of our common stock borrowed by a forward purchaser (or its affiliate) and sold through a forward
seller.
Sales of our common stock, if any, under this prospectus supplement and the accompanying prospectus may be made in negotiated
transactions or transactions that are deemed to be at the market offerings as defined in Rule 415 under the Securities Act of 1933, as amended, or the Securities Act, including sales made by means of ordinary brokers transactions,
including directly on the New York Stock Exchange, or the NYSE, or sales made to or through a market maker other than on an exchange. No sales agent is required to sell any specific number or dollar amount of shares of our common stock but will use
its commercially reasonable efforts consistent with its normal trading and sales practices and subject to the terms of the equity distribution agreement and, in the case of shares offered through such sales agent as forward seller, the relevant
forward sale agreement to sell the shares of our common stock offered by this prospectus supplement, as instructed by us and, in the case of shares offered through such sales agent as forward seller, the relevant forward purchaser. Our common stock
to which this prospectus supplement relates will be sold only through one sales agent on any given day. The offering of our common stock pursuant to the equity distribution agreement will terminate upon the earlier of (1) the sale of our common
stock having an aggregate offering price of $300,000,000 or (2) the termination of the equity distribution agreement pursuant to the terms thereof.