QBIO Q BioMed Inc (CE)

* 3,174,091 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

** Calculation based on 31,772,679 outstanding shares of issuer’s Common Stock, consisting of 28,598,588 shares of Common Stock outstanding shares as of the date of this report and an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

* 3,174,091 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

** Calculation based on 31,772,679 outstanding shares of issuer’s Common Stock, consisting of 28,598,588 shares of Common Stock outstanding shares as of the date of this report and an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

* 3,174,091 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

** Calculation based on 31,772,679 outstanding shares of issuer’s Common Stock, consisting of 28,598,588 shares of Common Stock outstanding shares as of the date of this report and an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

* 3,174,091 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

** Calculation based on 31,772,679 outstanding shares of issuer’s Common Stock, consisting of 28,598,588 shares of Common Stock outstanding shares as of the date of this report and an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

* 3,174,091 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

** Calculation based on 31,772,679 outstanding shares of issuer’s Common Stock, consisting of 28,598,588 shares of Common Stock outstanding shares as of the date of this report and an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

* 3,174,091 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

** Calculation based on 31,772,679 outstanding shares of issuer’s Common Stock, consisting of 28,598,588 shares of Common Stock outstanding shares as of the date of this report and an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

* 3,174,091 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

** Calculation based on 31,772,679 outstanding shares of issuer’s Common Stock, consisting of 28,598,588 shares of Common Stock outstanding shares as of the date of this report and an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

* 3,174,091 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

** Calculation based on 31,772,679 outstanding shares of issuer’s Common Stock, consisting of 28,598,588 shares of Common Stock outstanding shares as of the date of this report and an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

* 3,174,091 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

** Calculation based on 31,772,679 outstanding shares of issuer’s Common Stock, consisting of 28,598,588 shares of Common Stock outstanding shares as of the date of this report and an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

* 3,174,091 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

** Calculation based on 31,772,679 outstanding shares of issuer’s Common Stock, consisting of 28,598,588 shares of Common Stock outstanding shares as of the date of this report and an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

* 3,174,091 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

** Calculation based on 31,772,679 outstanding shares of issuer’s Common Stock, consisting of 28,598,588 shares of Common Stock outstanding shares as of the date of this report and an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

* 3,174,091 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

** Calculation based on 31,772,679 outstanding shares of issuer’s Common Stock, consisting of 28,598,588 shares of Common Stock outstanding shares as of the date of this report and an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

Item 1.

c/o Ortoli Rosenstadt LLP

366 Madison Avenue, 3nd Floor

New York, NY

1012 Springfield Ave.

Mountainside, NJ 07092

Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1.

* 3,174,091 shares consisting of direct ownership of 0 shares of Common Stock plus the deemed ownership of an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

** Calculation based on 31,772,679 outstanding shares of issuer’s Common Stock, consisting of 28,598,588 shares of Common Stock outstanding shares as of the date of this report and an additional 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report.

If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following [ ].

The reporting persons directly or indirectly own an aggregate of 3,174,091, or 9.99%, shares of Common Stock of the Company as of the date of this filing. YA II and the other reporting persons shared the power to vote and dispose any such Common Stock.

Direct beneficial ownership of such Common Stock by the reporting persons is as follows (and therefore excludes any Common Stock indirectly held by such person or any securities, such as warrants, which may be exercised or converted into Common Stock of the Company):

In addition to the direct beneficial ownership set forth above, each reporting person is also deemed to be the indirect beneficial owner of additional Common Stock that may be acquired by each such reporting person within 60 days of the date of this filing (such that YA II PN, Ltd., D-Beta One EQ, Ltd. and SC-Sigma Global Partners, LP are deemed to be the direct and indirect beneficial owner of an aggregate of 3,174,091). Such Common Stock may be acquired by the reporting persons upon the conversion of shares of a Convertible Debenture (the “CD”) with an outstanding principal balance of approximately $500,000 and/or 227,997 shares Series A Preferred Stock and/or 503,134 shares Series B Preferred Stock (collectively, the “Preferred Shares”) as of the date of this filing, all of which are convertible or exercisable into the Company’s Common Stock. However, the issuance of such Common Stock is subject to an ownership cap that limits the number of shares of Common Stock that may be issued upon conversion of the CD and/or Preferred Shares to a total of 9.99% of the Company’s outstanding Common Stock. Accordingly, the direct and indirect beneficial ownership of the Company’s Common Stock by all reporting persons is limited to an aggregate of 3,174,091 shares, which is equal to 9.99% of the Company’s outstanding Common Stock of 28,598,588 shares (the most recent outstanding Common Stock as reported by the Company), plus 3,174,091 shares of Common Stock that the reporting person has the right to acquire within 60 days of the date of the report. In calculating the number of shares of Common Stock that may be subject to the ownership cap, the number of shares of Common Stock beneficially owned by the holder of the CD and/or Preferred Shares and all of its affiliates are taken into consideration. Solely for purposes of this filing, all of the reporting persons are deemed to be affiliated parties and therefore any shares of Common Stock beneficially owned by one reporting person are deemed to be held by all other reporting persons.

Below is a description of the relationship among the reporting persons:

YA II PN, Ltd. (“YA II”) is beneficially owned by YA Global Investments II (U.S.), LP (the “YA Feeder”). Yorkville Advisors Global, LP (the “YA Advisor”) is the investment manager to YA II. Yorkville Advisors Global II, LLC (the “YA Advisor GP”) is the general partner to the YA Advisor. YAII GP, LP (the “YA GP”) is the general partner to the YA Feeder. YAII GP II, LLC (the “Yorkville GP”) is the general partner to the YA GP. Mark Angelo makes the investment decisions on behalf of YA II. Accordingly, each of YA II, YA Feeder, the YA Advisor, the YA Advisor GP, the YA GP, the Yorkville GP and Mark Angelo may be deemed affiliates and therefore may be deemed to beneficially own the same number of shares of Common Stock.

D-Beta One EQ, Ltd. (“D-Beta”) is beneficially owned by D-Beta One Blocker EQ, Ltd. (“Blocker”), which is beneficially owned by D-Beta One Growth and Opportunity Fund Offshore, LP (the “Opportunity Fund”). D-Beta One GP, LP (D-Beta GP”) is the general partner to the Opportunity Fund. D-Beta One GP, LLC (“D-B GP”) is the general partner to the D-Beta GP. YA Advisor is the investment manager to D-Beta. Mark Angelo makes the investment decisions on behalf of D-Beta. Accordingly, each of D-Beta, the Blocker, the Opportunity Fund, the D-Beta GP, the D-B GP, YA Advisor, and Mark Angelo may be deemed affiliates and therefore may be deemed to beneficially own the same number of shares of Common Stock.

SC-Sigma Global Partners, LP (“SC-Sigma”) is beneficially owned by the D-Beta GP. The D-B GP is the general partner of the D-Beta GP. The YA Advisor is the investment manager to SC-Sigma. Accordingly, SC-Sigma, the D-Beta GP, the D-B GP, the YA Advisor, and Mark Angelo may be deemed affiliates and therefore may be deemed to beneficially own the same number of shares of Common Stock.

For purposes of this filing, each of the reporting persons is deemed an affiliate of each other reporting person. YA II, D-Beta and SC-Sigma may be deemed affiliates through having a common investment manager, through D-Beta and SC-Sigma having common ownership, and through having common ownership of the three private funds’ general partners (the YA Advisor GP, the YA GP, the Yorkville GP, the D-Beta GP and the D-B GP).

Not Applicable

See Item 6.

Not Applicable

By signing below, I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as participant in any transaction having that purpose or effect.

Additional Information:

Each Reporting Person disclaims beneficial ownership of any securities beneficially owned by each other Reporting Person, and its report shall not be deemed to be an admission that any Reporting Person is the beneficial owner of these securities for the purpose of Section 16 or for any other purpose.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement in true, complete and correct.