Boston Life Sciences Sponsors Movement Disorder Society's 1st Annual Neuroimaging in Parkinson's Disease Symposium
01 Febrero 2007 - 10:07AM
PR Newswire (US)
HOPKINTON, Mass., Feb. 1 /PRNewswire-FirstCall/ -- Boston Life
Sciences, Inc. (NASDAQ:BLSI) announced today that it will be a
major sponsor of the 1st Annual Neuroimaging in Parkinson's Disease
Symposium. The symposium will be held on February 2nd - 3rd, 2007,
in Innsbruck, Austria, under the auspices of The Movement Disorder
Society. Dr. Mark Hurtt, Chief Medical Officer of Boston Life
Sciences, commented, "Until now, Boston Life Sciences has been
developing ALTROPANE(R) molecular imaging agent in the U.S. only.
Given the positive results from the POET-1 trial announced in
September 2006, we are seeking to advance ALTROPANE on a global
basis. We believe that this meeting will allow us to elevate
ALTROPANE's profile in Europe and foster relationships with
European leaders in nuclear medicine and Parkinson's Disease, or
PD, with the goal of accelerating the launch and expansion of our
ALTROPANE clinical program in Europe later this year." The program
for the symposium features a faculty of leading international PD
experts who will discuss the potential of different imaging
modalities and techniques based on nuclear medicine and magnetic
resonance imaging, as well as ultrasound technology as they relate
to research, clinical diagnoses, monitoring of disease progression
and monitoring treatment interventions of patients with
Parkinsonism. The Executive Organizing Committee of the symposium
consists of Werner Poewe, MD, Kenneth Marek, MD and Eduardo Tolosa,
MD, FRCP, all noted experts in PD and neuroimaging. About
ALTROPANE(R) Molecular Imaging Agent ALTROPANE ([I-123]-E-IACFT
Injection) is a molecular imaging agent that specifically binds to
the dopamine transporter (DAT) protein found on the surface of
dopamine-producing neurons, making it visible during Single Photon
Emission Computed Tomography, or SPECT, imaging. Since most forms
of Parkinsonian Syndromes (PS) result in a decreased number of
dopamine-producing cells, it would be expected that these patients
also have fewer DATs than do patients without PS. Thus, we believe
that ALTROPANE used in conjunction with SPECT imaging could be a
useful test to distinguish Parkinsonian Syndrome tremors from
non-Parkinsonian tremor: non-Parkinsonian patients would have more
ALTROPANE-binding visible in the SPECT image, while Parkinsonian
patients would have less. In September 2006, BLSI reported the
results from the ALTROPANE Phase III trial, POET-1. These results
demonstrated that ALTROPANE showed statistically significant
superiority over the diagnosis of a primary care physician on
measures of both specificity and sensitivity. Experts estimate that
each year approximately 140,000 individuals present to their
physician with new, undiagnosed movement disorders such as
Parkinson's Disease and Essential Tremor. The International
Essential Tremor Foundation estimates that as many as 10 million
people in the United States are afflicted by Essential Tremor. In
2002, the European Journal of Neurology reported that there is a
20- to 30-percent misdiagnosis rate in the early stages of
Parkinson's disease. Other publications have reported even higher
rates of misdiagnosis. We believe that the accurate differentiation
of Parkinsonian from non-Parkinsonian tremors has important
clinical implications. Physicians may be able to initiate earlier
referral for specialty care, prescribe effective treatments, and
provide a more-informed prognosis for patients and their families.
If these trials are successful and the drug is approved, we believe
that ALTROPANE could be a highly-selective CNS diagnostic molecular
imaging agent -- a valuable tool to help clinicians make better,
more-accurate diagnoses. About Boston Life Sciences Boston Life
Sciences, Inc. (BLSI) is engaged in the research and clinical
development of diagnostic and therapeutic products for central
nervous system (CNS) disorders. ALTROPANE(R) molecular imaging
agent is currently in Phase III clinical trials for the diagnosis
of Parkinson's Disease (PD) and in Phase II clinical trials for the
diagnosis of Attention Deficit Hyperactivity Disorder (ADHD).
Cethrin(R), a recombinant protein drug designed to promote nerve
repair after acute spinal cord injury, has reported positive
interim results in a Phase I/IIa clinical trial in the U.S. and
Canada. The company's research and pre-clinical CNS programs
include Inosine for the treatment of spinal cord injury and stroke,
a DAT blocker for the treatment of Parkinson's disease, and a
second generation technetium-based molecular imaging agent for PD
and ADHD. BLSI's current research collaborations include Harvard
Medical School and Children's Hospital Boston. Safe Harbor The
foregoing release contains certain forward-looking statements
within the meaning of the Private Securities Litigation Reform Act
of 1995. Forward- looking statements include statements regarding
Boston Life Sciences' future expectations, beliefs, intentions,
goals, strategies, plans or prospects regarding the future,
including the development of the ALTROPANE clinical program, and
the breadth of the Company's technologies and intellectual property
portfolio. Forward-looking statements can be identified by
terminology such as "anticipate," "believe," "could," "could
increase the likelihood," "estimate," "expect," "intend," "is
planned," "may," "should," "will," "will enable," "would be
expected," "look forward," "may provide," "would" or similar terms,
variations of such terms or the negative of those terms. Such
forward-looking statements involve known and unknown risks,
uncertainties and other factors including those risks,
uncertainties and factors referred to in the Company's Quarterly
Report on Form 10-Q for the quarter ended September 30, 2006 filed
with the Securities and Exchange Commission under the section "Risk
Factors," as well as other documents that may be filed by Boston
Life Sciences from time to time with the Securities and Exchange
Commission. As a result of such risks, uncertainties and factors,
the Company's actual results may differ materially from any future
results, performance or achievements discussed in or implied by the
forward-looking statements contained herein. Boston Life Sciences
is providing the information in this press release as of this date
and assumes no obligations to update the information in this press
release. Contact: Sharon Correia of Boston Life Sciences, Inc.,
+1-508-497-2360, ext. 224 DATASOURCE: Boston Life Sciences, Inc.
CONTACT: Sharon Correia of Boston Life Sciences, Inc.,
+1-508-497-2360, ext. 224 Web site:
http://www.bostonlifesciences.com/
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